(3-fluoro-5-methylphenyl)boronic acid
Product Information
Molecular Formula
C7H8BFO2
Molecular Weight
153.95
Description
(3-fluoro-5-methylphenyl)boronic acid is a pharmaceutical intermediate often utilized in the development of drugs treating oncological disorders. It plays a fundamental role in Suzuki coupling reactions, aiding in the synthesis of biologically active compounds.
Synonyms
3-Fluoro-5-methylbenzeneboronic acid; (3-FLUORO-5-METHYLPHENYL)BORONICACID; 5-Fluoro-3-methylphenylboronic acid; (3-fluoranyl-5-methyl-phenyl)boronic acid; (3-fluoro-5-methylphenyl)boronic acid; 3-Fluoro-5-methylphenylboronic Acid (contains varying amounts of Anhydride); N,N-BIS(1-HEXYLHEPTYL)-PERYLENE-3,4:9,10-BIS-(DICARBOXIMIDE)
IUPAC Name
(3-fluoro-5-methylphenyl)boronic acid
SMILES
B(C1=CC(=CC(=C1)F)C)(O)O
InChI
InChI=1S/C7H8BFO2/c1-5-2-6(8(10)11)4-7(9)3-5/h2-4,10-11H,1H3
InChI Key
QQPLHUGOUZKARP-UHFFFAOYSA-N
Flash Point
Not applicable
Computed Properties
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
3
Rotatable Bond Count
1
Exact Mass
154.0601378 g/mol
Monoisotopic Mass
154.0601378 g/mol
Topological Polar Surface Area
40.5Ų
Heavy Atom Count
11
Formal Charge
0
Complexity
132
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-114042069-A | 5-substituted pyridazine-4-amine derivative, preparation method and application | 2021-10-22 |
| WO-2021144440-A1 | Quinoxaline derivatives as modulators of the glucocorticoid receptor | 2020-01-17 |
| WO-2021063914-A1 | 4-quinolinone antibacterial compounds | 2019-09-30 |
| WO-2021007477-A1 | Indazoles and azaindazoles as lrrk2 inhibitors | 2019-07-11 |
| CA-3145305-A1 | Indazoles and azaindazoles as lrrk2 inhibitors | 2019-07-11 |
| CA-3143103-A1 | Pyridine carbamates and their use as glun2b receptor modulators | 2019-06-14 |
| CN-114007691-A | Pyridine carbamates and their use as GluN2B receptor modulators | 2019-06-14 |
| KR-20220020916-A | Pyridine carbamates and their use as GluN2B receptor modulators | 2019-06-14 |
| TW-202102504-A | Isochromene derivatives as phosphoinositide 3-kinases inhibitors | 2019-04-04 |
| US-2020102303-A1 | Monoacylglycerol Lipase Modulators | 2018-09-28 |
