4,4'-cyclohexylidenedianiline
Product Information
Molecular Formula
C18H22N2
Molecular Weight
266.3807
Description
4,4'-cyclohexylidenedianiline can effectively impedes the proliferation of malignant cells, thereby showcasing promise as a therapeutic agent against multiple cancerous ailments.
Synonyms
3282-99-3; 1,1-Bis(4-aminophenyl)cyclohexane; 4,4'-Cyclohexylidenedianiline; 4,4'-cyclohexane-1,1-diyldianiline; 4,4'-(Cyclohexane-1,1-diyl)dianiline; 4,4'-Cyclohexylidenedionline
IUPAC Name
4-[1-(4-aminophenyl)cyclohexyl]aniline
SMILES
C1CCC(CC1)(C2=CC=C(C=C2)N)C3=CC=C(C=C3)N
InChI
InChI=1S/C18H22N2/c19-16-8-4-14(5-9-16)18(12-2-1-3-13-18)15-6-10-17(20)11-7-15/h4-11H,1-3,12-13,19-20H2
InChI Key
ZSQIQUAKDNTQOI-UHFFFAOYSA-N
Boiling Point
473.1°C at 760mmHg
Melting Point
110°C
Purity
95%
Density
1.112g/cm3
Solubility
36 [ug/mL] (The mean of the results at pH 7.4)
Appearance
White to Yellow to Orange powder to crystal
Safety Information
Hazards
H315:
Causes skin irritation.
H319:
Causes serious eye irritation.
Causes skin irritation.
H319:
Causes serious eye irritation.
Precautionary Statement
P264:
Wash thoroughly after handling.
P280:
Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:
IF ON SKIN:
Wash with plenty of soap and water.
P332+P313:
If skin irritation occurs:
Get medical advice/attention.
P337+P313:
If eye irritation persists:
Get medical advice/attention.
P362+P364:
Take off contaminated clothing. [As modified by IV ATP].
And wash it before reuse. [Added by IV ATP].
Wash thoroughly after handling.
P280:
Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:
IF ON SKIN:
Wash with plenty of soap and water.
P332+P313:
If skin irritation occurs:
Get medical advice/attention.
P337+P313:
If eye irritation persists:
Get medical advice/attention.
P362+P364:
Take off contaminated clothing. [As modified by IV ATP].
And wash it before reuse. [Added by IV ATP].
Computed Properties
XLogP3
4.8
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
2
Rotatable Bond Count
2
Exact Mass
266.178298710 g/mol
Monoisotopic Mass
266.178298710 g/mol
Topological Polar Surface Area
52Ų
Heavy Atom Count
20
Formal Charge
0
Complexity
269
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-113321807-A | Preparation method of crown ether-containing copolymerized polyimide and phosphoric acid-doped proton exchange membrane thereof | 2021-06-15 |
| CN-113150545-A | Polymer film containing nano fullerene and preparation method thereof | 2020-12-30 |
| CN-112028853-A | Arylamine derivative and organic electroluminescent device thereof | 2020-09-09 |
| CN-112028853-B | Arylamine derivative and organic electroluminescent device thereof | 2020-09-09 |
| WO-2022034907-A1 | Metal patterning material, amine compound, electronic device, and method for forming metal pattern | 2020-08-12 |
| JP-2022019614-A | Liquid crystal polymer, composition for heat dissipation member using it, material for electronic parts | 2020-07-16 |
| JP-2022008158-A | Epoxy resin compositions, compositions for electronic components, materials for electronic components | 2020-06-24 |
| JP-2021195506-A | Compositions for electronic components and materials for electronic components | 2020-06-18 |
| JP-2021195393-A | Polyamic acid varnish precursor, polyamic acid varnish, polyimide membrane, enamel wire, motor | 2020-06-10 |
| JP-2021193176-A | Polymerizable compounds, compositions for electronic components, materials for electronic components | 2020-06-08 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 22059004 | 2011-09-01 | 4,4'-(Cyclo-hexane-1,1-di-yl)dianilinium dichloride monohydrate | Acta crystallographica. Section E, Structure reports online |
| 16505906 | 2006-03-14 | A new twist in anion binding: metallo-helicate hosts for anionic guests | Dalton transactions (Cambridge, England : 2003) |
