4-AMINO-1,8-NAPHTHALIC ANHYDRIDE
Product Information
Molecular Formula
C12H8N2O2
Molecular Weight
212.20
Description
4-AMINO-1,8-NAPHTHALIC ANHYDRIDE is a key component in the synthesis of various pharmaceuticals and dyes. With its aromatic structure, it finds applications in the development of drugs targeting cancer and autoimmune diseases. Its versatility also extends to the creation of dyes used in industries such as textiles and electronics.
Synonyms
6-AMINO-BENZO[DE]ISOQUINOLINE-1,3-DIONE; 4-AMINO-1,8-NAPHTHALIC ANHYDRIDE; 4-AMINO-1,8-NAPHTHALIMIDE; 4-ANI; TIMTEC-BB SBB000529; TIMTEC-BB SBB003425; 4-aminonaphthalene-1,8-dicarboxylic anhydride; 6-Aminobenz[de]isochromene-1,3-dione
IUPAC Name
8-amino-3-oxatricyclo[7.3.1.05,13]trideca-1(12),5(13),6,8,10-pentaene-2,4-dione
SMILES
C1=CC2=C(C=CC3=C2C(=C1)C(=O)OC3=O)N
InChI
InChI=1S/C12H7NO3/c13-9-5-4-8-10-6(9)2-1-3-7(10)11(14)16-12(8)15/h1-5H,13H2
InChI Key
QIXHMCMCFSNKOG-UHFFFAOYSA-N
Purity
0.95
Density
1.105 g/mL at 25 °C(lit.)
Safety Information
Hazards
H302 + H312 + H332 - H315 - H319 - H335 - H350
Precautionary Statement
P201 - P280 - P301 + P312 + P330 - P302 + P352 + P312 - P304 + P340 + P312 - P308 + P313
Computed Properties
XLogP3
1.9
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
4
Rotatable Bond Count
0
Exact Mass
213.042593085 g/mol
Monoisotopic Mass
213.042593085 g/mol
Topological Polar Surface Area
69.4Ų
Heavy Atom Count
16
Formal Charge
0
Complexity
341
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-113354584-A | Naphthalimide fluorescent probe for distinguishing Cys, Hcy and GSH, and preparation method and application thereof | 2021-06-15 |
| CN-112521738-A | Degradable light conversion film and preparation method and application thereof | 2020-12-16 |
| CN-112521738-B | Degradable light conversion film and preparation method and application thereof | 2020-12-16 |
| WO-2021231998-A1 | High-temperature, thermally-insulative laminates including aerogel layers | 2020-05-15 |
| WO-2021232001-A1 | Low-dielectric constant, low-dissipation factor laminates including aerogel layers | 2020-05-15 |
| WO-2021217073-A2 | Air permeable filter material comprising a polymer aerogel | 2020-04-24 |
| WO-2020198264-A1 | Modified cleavases, uses thereof and related kits | 2019-03-26 |
| US-2021214701-A1 | Modified cleavases, uses thereof and related kits | 2019-03-26 |
| CA-3134776-A1 | Modified cleavases, uses thereof and related kits | 2019-03-26 |
| CN-113993997-A | Modified cleaving enzymes, uses thereof and related kits | 2019-03-26 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 17070119 | 2007-03-01 | Assessment of 4-nitro-1,8-naphthalic anhydride reductase activity in homogenates of bakers' yeast by reversed-phase high-performance liquid chromatography | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences |
| 16851591 | 2005-03-30 | Aminonaphthalic anhydrides as red-emitting materials: electroluminescence, crystal structure, and photophysical properties | The journal of physical chemistry. B |
| 5819 | 1975-10-17 | [Clinical experiences with the Kö 1366 (Bunitrololhydrochloride) beta receptor blockader and the combination Kö 1366/Isosorbitdinitrate in patients with coronary disease] | Wiener medizinische Wochenschrift (1946) |
