4-Aminophenylboronic Acid Pinacol Ester

Product Information

Molecular Formula:
C12H18NO2B
Molecular Weight:
219.09
Description
Reagent used for: Suzuki-Miyaura cross-coupling reactions ; Mercury(II) detection by fluorometry with new fluorogenic indicators based on through-bond energy transfer from pentaquinone to rhodamine ; Rhodium-catalyzed amination reactions ; Palladium-catalyzed Suzuki cross-coupling to synthesize potential antitubercular and antimicrobial compounds Reagent used in Preparation of ; Hexaphenylbenzene derivatives as a potential bioprobe and multichannel keypad system; Pyromellitic diimide-based polymer as matrix for solution-processable n-channel field-effect transistors ; Alternating copolymers of oligoarylenes and naphthalene bisimides as low band gap semiconductors with electrochemical and spectroelectrochemical behavior ; γ-secretase modulators in the treatment of Amyloid β formation.
Synonyms
4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline; 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline
IUPAC Name
4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline
Canonical SMILES
B1(OC(C(O1)(C)C)(C)C)C2=CC=C(C=C2)N
InChI
InChI=1S/C12H18BNO2/c1-11(2)12(3,4)16-13(15-11)9-5-7-10(14)8-6-9/h5-8H,14H2,1-4H3
InChI Key
ZANPJXNYBVVNSD-UHFFFAOYSA-N
Boiling Point
340 °C at 760 mmHg
Melting Point
165-169 °C (lit.)
Purity
97 %
Density
1.05 g/cm3
LogP
2.14920

Safety Information

Hazards
H315 - H319 - H335
Precautionary Statement
P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501
Signal Word
Warning

Computed Properties

Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
3
Rotatable Bond Count
1
Exact Mass
219.1430590 g/mol
Monoisotopic Mass
219.1430590 g/mol
Topological Polar Surface Area
44.5Ų
Heavy Atom Count
16
Formal Charge
0
Complexity
244
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes

Patents

Publication Number Title Priority Date
CN-113929635-A 1, 6-diphenyl-1H-benzo [ d ] [1,2,3] triazole compound and preparation method and application thereof 2021-11-09
CN-113663733-A Preparation and application of graphene covalent load bipyridine metal complex catalyst 2021-09-15
CN-113851599-A Organic electroluminescent device and display device comprising same 2021-09-13
CN-113823750-A Organic electroluminescent device and display device comprising same 2021-08-10
CN-113443999-A Benzene liquid crystal compound and preparation method thereof 2021-08-02
CN-113387817-A Fluorine-containing aromatic diamine compound, preparation method thereof and colorless transparent polyimide film 2021-07-27
CN-113045559-A Diaryl urea PI3K alpha/mTOR double-target inhibitor and pharmaceutical composition and application thereof 2021-03-15
CN-112939964-A Benzo-heterocycle substituted phenanthridine quaternary ammonium salt derivative and preparation method and application thereof 2021-03-09
CN-112898568-A Conjugated microporous polymer based on 1,3,6, 8-tetra (4-aminophenyl) pyrene and preparation method thereof 2021-02-06
CN-113045582-A PARP-1/PI3K double-target inhibitor or pharmaceutically acceptable salt thereof, and preparation method and application thereof 2021-02-05

Literatures

PMID Publication Date Title Journal
21336331 2011-03-01 Palladium-mediated intracellular chemistry Nature chemistry
17922005 2007-11-01 ATP-competitive inhibitors of the mitotic kinesin KSP that function via an allosteric mechanism Nature chemical biology
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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