[4-(morpholinomethyl)phenyl]boronic acid
Product Information
Molecular Formula
C11H16BNO3
Molecular Weight
221.06
Description
[4-(Morpholinomethyl)phenyl]boronic acid is a pharmaceutical intermediate widely used in drug synthesis. In particular, it aids in the production of effective anti-cancer drugs, primarily promoting research in the treatment of various forms of leukemia and lymphoma.
Synonyms
4-(4-MORPHOLINYLMETHYL)PHENYLBORONIC ACID; 4-(MORPHOLINYLMETHYL)PHENYLBORONIC ACID; [4-(morpholin-4-ylmethyl)phenyl]boronic Acid; (4-(morpholinomethyl)phenyl)boronic acid; [4-(morpholinomethyl)phenyl]boronic acid; {4-[(Morpholin-4-yl)methyl]phenyl}boronic acid; Boronic acid, [4-(4-morpholinylmethyl)phenyl]-; MFCD06801707; 4-(4-Morpholinomethyl)phenylboronic Acid; 4-(Morpholinomethyl)phenylboronicacid; (4-(morpholinomethyl)pbenyl)boronic acid; SY104543; (4-(morpholino methyl)phenyl)boronic acid; (4-(morpholinomethyl)phenyl) boronic acid
IUPAC Name
[4-(morpholin-4-ylmethyl)phenyl]boronic acid
SMILES
B(C1=CC=C(C=C1)CN2CCOCC2)(O)O
InChI
InChI=1S/C11H16BNO3/c14-12(15)11-3-1-10(2-4-11)9-13-5-7-16-8-6-13/h1-4,14-15H,5-9H2
InChI Key
QPFDUULIDNELSE-UHFFFAOYSA-N
Flash Point
Not applicable
Safety Information
Hazards
H318
Precautionary Statement
P280 - P305 + P351 + P338
Computed Properties
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
4
Rotatable Bond Count
3
Exact Mass
221.1223235 g/mol
Monoisotopic Mass
221.1223235 g/mol
Topological Polar Surface Area
52.9Ų
Heavy Atom Count
16
Formal Charge
0
Complexity
201
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-113861188-A | Pyrazolo [3,4-b ] pyridine derivative, preparation method thereof and application thereof as HPK1 inhibitor | 2021-08-23 |
| CN-112094266-A | Pyrrolopyridinone compound, preparation method, composition and application thereof | 2019-06-17 |
| WO-2020253711-A1 | Pyrrolopyridone compound, preparation method therefor, and composition and use thereof | 2019-06-17 |
| CA-3141549-A1 | Substituted naphthalene diimides and their use | 2019-05-16 |
| CN-114026089-A | Substituted naphthalene diimides and their use | 2019-05-16 |
| WO-2020210630-A1 | Tricyclic degraders of ikaros and aiolos | 2019-04-12 |
| AU-2020272978-A1 | Tricyclic degraders of Ikaros and Aiolos | 2019-04-12 |
| CN-113677664-A | Tricyclic degradants of IKAROS and AIOLOS | 2019-04-12 |
| EP-3953332-A1 | Tricyclic degraders of ikaros and aiolos | 2019-04-12 |
| KR-20210152515-A | Tricyclic disintegrants of Ikaros and Aiolos | 2019-04-12 |
