4'-Phenoxyacetophenone
Product Information
Molecular Formula
C14H12O2
Molecular Weight
212.25
Description
4'-Hydroxyacetophenone has been used as ketone component in the preparation of 1-aryl-3-phenethylamino-1-propanone hydrochlorides, potential cytotoxic agents, via Mannich reactions.
Synonyms
1-(4-phenoxyphenyl)ethanone; 1-(4-phenoxyphenyl)ethanone
IUPAC Name
1-(4-phenoxyphenyl)ethanone
SMILES
CC(=O)C1=CC=C(C=C1)OC2=CC=CC=C2
InChI
InChI=1S/C14H12O2/c1-11(15)12-7-9-14(10-8-12)16-13-5-3-2-4-6-13/h2-10H,1H3
InChI Key
DJNIFZYQFLFGDT-UHFFFAOYSA-N
Boiling Point
200 °C / 12 mmHg (lit.)
Flash Point
235.4 °F
Purity
98 %
Density
1.108 g/cm3
Refractive Index
n20/D 1.533 (lit.)
LogP
3.68150
Safety Information
Precautionary Statement
P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501
Signal Word
Warning
Computed Properties
XLogP3
3.4
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
2
Rotatable Bond Count
3
Exact Mass
212.083729621 g/mol
Monoisotopic Mass
212.083729621 g/mol
Topological Polar Surface Area
26.3Ų
Heavy Atom Count
16
Formal Charge
0
Complexity
223
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-114057626-A | Indole-2, 3-dione derivative, preparation method thereof and anti-liver cancer drug for inhibiting RECQL4 specific expression | 2021-12-07 |
| CN-112877053-A | Medium-high temperature corrosion inhibitor for acid fracturing and preparation method thereof | 2021-01-18 |
| WO-2022047394-A1 | 3d printed composites from phase separated materials | 2020-08-31 |
| US-2022056161-A1 | Articles comprising crosslinked polymer network comprising thioether crosslinks and process of making and using same | 2020-08-21 |
| WO-2022032236-A2 | Polymeric composite membranes having oriented nanochannels and methods of making the same | 2020-08-07 |
| WO-2022023737-A1 | Additive manufacturing composition for 3-d printed object | 2020-07-28 |
| CN-212739467-U | A change material device for famoxadone production | 2020-07-14 |
| WO-2022012550-A1 | Substituted 1h-imidazo [1, 2-b] pyrazole-3-carboxamide as bruton's tyrosine kinase inhibitors | 2020-07-13 |
| EP-3936572-A1 | Method for preparing a 3d-printed silicone | 2020-07-10 |
| WO-2022008721-A1 | Method for preparing a 3d-printed silicone | 2020-07-10 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 4318071 | 1970-07-01 | Antiviral phenoxathiins and their analogs. Study of the structure-activity relationships for antiviral activity and the replacement ability in poliovirus type 3 dependent variants | Journal of medicinal chemistry |
