9-methylidenefluorene
| Catalog Number | Size | Price | Stock | Quantity |
|---|---|---|---|---|
| BPM-145813 | 500 mg | $439 | In stock |
Product Information
Molecular Formula
C14H10
Molecular Weight
178.23
Description
9-Methylidenefluorene is an analog of 9-Methylfluorene; a compound that has been shown to be mutagenic in Salmonella typhimurium TA98 and TA100 in the presence of 9000 X g supernantant from Aroclor-induced rats.
Synonyms
9-Methylene-9H-fluorene; 9H-Fluorene, 9-Methylene-; Fluorenylidenemethane; 9-Methylene-fluorene
IUPAC Name
9-methylidenefluorene
SMILES
C=C1C2=CC=CC=C2C3=CC=CC=C13
InChI
InChI=1S/C14H10/c1-10-11-6-2-4-8-13(11)14-9-5-3-7-12(10)14/h2-9H,1H2
InChI Key
ZYASLTYCYTYKFC-UHFFFAOYSA-N
Boiling Point
305.9±12.0 °C (Predicted)
Melting Point
46-48 °C
Density
1.12±0.1 g/cm3(Predicted)
Appearance
Solid
Storage
Amber Vial, -20 °C Freezer, Under inert atmosphere
Safety Information
Hazards
H302:
Harmful if swallowed.
H401:
Toxic to aquatic life.
H411:
Toxic to aquatic life with long-lasting effects.
Harmful if swallowed.
H401:
Toxic to aquatic life.
H411:
Toxic to aquatic life with long-lasting effects.
Precautionary Statement
P273:
Avoid release to the environment.
P301:
IF SWALLOWED:
P312:
Call a POISON CENTER or doctor/physician if you feel unwell.
Avoid release to the environment.
P301:
IF SWALLOWED:
P312:
Call a POISON CENTER or doctor/physician if you feel unwell.
Computed Properties
XLogP3
3.7
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
0
Rotatable Bond Count
0
Exact Mass
178.078250319 g/mol
Monoisotopic Mass
178.078250319 g/mol
Topological Polar Surface Area
0Ų
Heavy Atom Count
14
Formal Charge
0
Complexity
216
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-113354514-A | Method for controllable high-selectivity synthesis of 9-fluorenylmethanol and 9, 9-bis (hydroxymethyl) fluorene | 2021-06-07 |
| CN-112608222-A | Method for preparing aldehyde ketone compound by olefin oxidation | 2020-12-03 |
| CN-111362955-A | Organic compound and application thereof to OLED device | 2018-12-26 |
| US-2020016185-A1 | Senolytic compositions and uses thereof | 2018-07-11 |
| WO-2020014409-A1 | Senolytic compositions and uses thereof | 2018-07-11 |
| CA-3105982-A1 | Senolytic compositions and uses thereof | 2018-07-11 |
| CN-112469697-A | Anti-aging composition and application thereof | 2018-07-11 |
| EP-3790861-A1 | Senolytic compositions and uses thereof | 2018-07-11 |
| KR-20210030905-A | Senolytic composition and use thereof | 2018-07-11 |
| US-11026963-B2 | Senolytic compositions and uses thereof | 2018-07-11 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 22327299 | 2012-03-21 | Design of small molecule reagents that enable signal amplification via an autocatalytic, base-mediated cascade elimination reaction | Chemical communications (Cambridge, England) |
| 21210693 | 2011-02-03 | Controlling the spatial orientation of molecular actuators: polarized photoisomerization of 2-nitro-9-(2,2,2-triphenylethylidene)fluorene in a thin polymer matrix | The journal of physical chemistry. A |
| 20725626 | 2010-06-13 | Synthesis and g-quadruplex-binding properties of defined acridine oligomers | Journal of nucleic acids |
| 21140921 | 2010-01-01 | Thermal cleavage of the fmoc protection group | Chimia |
| 21197436 | 2010-01-01 | Synthesis of Peptides from α- and β-Tubulin Containing Glutamic Acid Side-Chain Linked Oligo-Glu with Defined Length | International journal of peptides |
| 16366613 | 2005-12-29 | Syntheses, structures, and photoisomerization of (E)- and (Z)-2-tert-butyl-9-(2,2,2-triphenylethylidene)fluorene | The journal of physical chemistry. A |
| 18969837 | 2005-01-30 | Measurement of the FMOC loading of protected amine-functionalised polymer beads | Talanta |
| 11552835 | 2001-09-19 | Dibenzofulvene, a 1,1-diphenylethylene analogue, gives a pi-stacked polymer by anionic, free-radical, and cationic catalysts | Journal of the American Chemical Society |
