Amino-PEG4-amine
Product Information
Molecular Formula
C10H24N2O4
Molecular Weight
236.31
Description
Amino-PEG4-C2-amine is a polyethylene glycol (PEG)-based PROTAC linker. Amino-PEG4-C2-amine can be used in the synthesis of a series of PROTACs.
Synonyms
3,6,9,12-Tetraoxatetradecane-1,14-diamine||||Triethylene Glycol Bis(2-aminoethyl) Ether
IUPAC Name
2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethanamine
SMILES
C(COCCOCCOCCOCCN)N
InChI
InChI=1S/C10H24N2O4/c11-1-3-13-5-7-15-9-10-16-8-6-14-4-2-12/h1-12H2
InChI Key
IFZOPNLVYZYSMQ-UHFFFAOYSA-N
Boiling Point
139 °C/0.2 mmHg
Flash Point
157 °C
Purity
>97.0%(GC)
Density
1.0±0.1 g/cm3
Solubility
In DMSO: 120 mg/mL (507.81 mM; Need ultrasonic)
In H2O: 120 mg/mL (507.81 mM; Need ultrasonic)
In H2O: 120 mg/mL (507.81 mM; Need ultrasonic)
Appearance
Colorless to Light yellow clear liquid
Storage
0-10°C
Safety Information
Hazards
H314:
Causes severe skin burns and eye damage.
Causes severe skin burns and eye damage.
Precautionary Statement
P280:
Wear protective gloves/protective clothing/eye protection/face protection.
P301+P330+P331:
IF SWALLOWED:
Rinse mouth.
Do NOT induce vomiting.
P303+P361+P353:
IF ON SKIN (or hair):
Take off immediately all contaminated clothing. [As modified by IV ATP].
Rinse skin with water/shower.
P304+P340+P310:
IF INHALED:
Remove person to fresh air and keep comfortable for breathing.
Immediately call a POISON CENTER or doctor/physician.
P305+P351+P338+P310:
IF IN EYES:
Rinse cautiously with water for several minutes.
Remove contact lenses if present and easy to do. Continue rinsing.
Immediately call a POISON CENTER or doctor/physician.
P501:
Dispose of contents/container in accordance with local/regional/national/international regulations.
Wear protective gloves/protective clothing/eye protection/face protection.
P301+P330+P331:
IF SWALLOWED:
Rinse mouth.
Do NOT induce vomiting.
P303+P361+P353:
IF ON SKIN (or hair):
Take off immediately all contaminated clothing. [As modified by IV ATP].
Rinse skin with water/shower.
P304+P340+P310:
IF INHALED:
Remove person to fresh air and keep comfortable for breathing.
Immediately call a POISON CENTER or doctor/physician.
P305+P351+P338+P310:
IF IN EYES:
Rinse cautiously with water for several minutes.
Remove contact lenses if present and easy to do. Continue rinsing.
Immediately call a POISON CENTER or doctor/physician.
P501:
Dispose of contents/container in accordance with local/regional/national/international regulations.
Computed Properties
XLogP3
-2.2
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
6
Rotatable Bond Count
13
Exact Mass
236.17360725 g/mol
Monoisotopic Mass
236.17360725 g/mol
Topological Polar Surface Area
89Ų
Heavy Atom Count
16
Formal Charge
0
Complexity
113
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-113593908-A | Aluminum electrolytic capacitor electrolyte, preparation method thereof and aluminum electrolytic capacitor | 2021-07-26 |
| CN-113174231-A | Polyimide resin composition, adhesive composition, and related articles | 2020-10-15 |
| JP-6881664-B1 | Polyimide resin composition, adhesive composition, film-like adhesive, adhesive sheet, copper foil with resin, copper-clad laminate, printed wiring board and polyimide film | 2020-10-15 |
| KR-102261516-B1 | Polyimide resin composition, adhesive composition, film-shaped adhesive material, adhesive sheet, copper foil with resin, copper clad laminate, printed wiring board and polyimide film | 2020-10-15 |
| WO-2022049236-A1 | Polymers containing repeating units with several metal or organic sulphonate units, methods for preparing same and uses thereof | 2020-09-03 |
| CN-112079743-A | Diamine, polyimide and polyimide film | 2020-08-26 |
| WO-2022028317-A1 | Antidiabetic compounds and compositions | 2020-08-05 |
| JP-6897856-B1 | Curable resin composition, cured product and laminate | 2020-04-17 |
| JP-2021169558-A | Film manufacturing method | 2020-04-15 |
| JP-2021169559-A | Method of manufacturing polyimide film | 2020-04-15 |
