Bis(dicyclohexylphosphinophenyl) ether
Product Information
Molecular Formula
C36H52OP2
Molecular Weight
562.75
Description
Catalyst for diastereoselective intramolecular N-arylation intermolecular carboamination
Synonyms
(Oxydi-2,1-phenylene)bis[dicyclohexyl] phosphine
IUPAC Name
dicyclohexyl-[2-(2-dicyclohexylphosphanylphenoxy)phenyl]phosphane
SMILES
C1CCC(CC1)P(C2CCCCC2)C3=CC=CC=C3OC4=CC=CC=C4P(C5CCCCC5)C6CCCCC6
InChI
InChI=1S/C36H52OP2/c1-5-17-29(18-6-1)38(30-19-7-2-8-20-30)35-27-15-13-25-33(35)37-34-26-14-16-28-36(34)39(31-21-9-3-10-22-31)32-23-11-4-12-24-32/h13-16,25-32H,1-12,17-24H2
InChI Key
HPFGZHCWLVSVKJ-UHFFFAOYSA-N
Melting Point
140-146 °C
Flash Point
Not applicable
Purity
97%
Safety Information
Hazards
H302 + H312 + H332 - H315 - H319 - H335
Precautionary Statement
P280 - P301 + P312 + P330 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338
Computed Properties
XLogP3
9.8
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
1
Rotatable Bond Count
8
Exact Mass
562.34934027 g/mol
Monoisotopic Mass
562.34934027 g/mol
Topological Polar Surface Area
9.2Ų
Heavy Atom Count
39
Formal Charge
0
Complexity
594
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-113548968-A | Method for synthesizing (Z) -olefin by nickel-catalyzed iron-mediated alkyne fluoroalkyl and product | 2021-07-21 |
| CN-112851661-A | Method for modularly and diversely synthesizing benzophenanthridine and protoberberine alkaloids | 2021-01-08 |
| WO-2021226114-A1 | Boronic acid derivatives and synthesis, polymorphic forms, and therapeutic uses thereof | 2020-05-05 |
| CN-113321639-A | Method for preparing polysubstituted isoquinolone derivative | 2020-02-28 |
| CN-112094165-A | Method for preparing biaryl compound by Suzuki coupling reaction | 2019-06-18 |
| CN-112047802-A | Polysubstituted ethylene compound, preparation method and application thereof | 2019-06-05 |
| WO-2020210613-A1 | Novel synthetic options towards the manufacture of (6r,10s)-10- {4-[5-chloro-2-(4-chloro-1h-1,2,3-triazol-1-yl)phenyl]-6-oxo-1(6h)- pyrimidinyl}- 1-(difluoromethyl)-6-methyl-1,4,7,8,9,10-hexahydro-11,15 -(metheno)pyrazolo [4,3-b] [1,7] diazacyclotetradecin-5(6h)-one | 2019-04-11 |
| TW-202104188-A | Novel synthetic options towards the manufacture of (6r,10s)-10-{4-[5-chloro-2-(4-chloro-1h-1,2,3-triazol-1-yl)phenyl]-6-oxo-1(6h)-pyrimidinyl}- 1-(difluoromethyl)-6-methyl-1,4,7,8,9,10-hexahydro-11,15-(metheno)pyrazolo[4,3-b][1,7]diazacyclotetradecin-5(6h)-one | 2019-04-11 |
| AU-2020272973-A1 | Novel synthetic options towards the manufacture of (6R,10S)-10- {4-[5-chloro-2-(4-chloro-1H-1,2,3-triazol-1-yl)phenyl]-6-oxo-1(6H)- pyrimidinyl}- 1-(difluoromethyl)-6-methyl-1,4,7,8,9,10-hexahydro-11,15 -(metheno)pyrazolo [4,3-b] [1,7] diazacyclotetradecin-5(6H)-one | 2019-04-11 |
| EP-3953334-A1 | Novel synthetic options towards the manufacture of (6r,10s)-10- {4-[5-chloro-2-(4-chloro-1h-1,2,3-triazol-1-yl)phenyl]-6-oxo-1(6h)- pyrimidinyl}- 1-(difluoromethyl)-6-methyl-1,4,7,8,9,10-hexahydro-11,15 -(metheno)pyrazolo [4,3-b] [1,7] diazacyclotetradecin-5(6h)-one | 2019-04-11 |
