Di-tert-butyl(methyl)phosphonium tetrafluoroborate
Product Information
Molecular Formula
C9H22BF4P
Molecular Weight
248.05
Description
Di-tert-butyl(methyl)phosphonium tetrafluoroborate may be used in the preparation of a precursor for nantenine analogs bearing a C4 phenyl substituent, which shows an affinity for 5-HT2B receptor. It may also be used in the palladium-catalyzed borylation of primary alkyl electrophiles (bromides, iodides or tosylates) using bis(pinacolato)diboron or bis(neopentyl glycolato)diboron as the boron source.
The phosphonium salt is used for Pd catalyzed cross coupling reaction.
The phosphonium salt is used for Pd catalyzed cross coupling reaction.
Synonyms
(t-Bu)2PMeHBF4,Bis(1,1-dimethylethyl)methylphosphine tetrafluoroborate
IUPAC Name
ditert-butyl(methyl)phosphaniumtetrafluoroborate
SMILES
[B-](F)(F)(F)F.CC(C)(C)[PH+](C)C(C)(C)C
InChI
InChI=1S/C9H21P.BF4/c1-8(2,3)10(7)9(4,5)62-1(3,4)5/h1-7H3/q-1/p+1
InChI Key
BRDLRXCAHKUWJS-UHFFFAOYSA-O
Melting Point
>230 °C (lit.)
Flash Point
Not applicable
Purity
97%
Safety Information
Hazards
H314
Precautionary Statement
P260 - P280 - P301 + P330 + P331 - P303 + P361 + P353 - P305 + P351 + P338 + P310
Computed Properties
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
5
Rotatable Bond Count
2
Exact Mass
248.1488305 g/mol
Monoisotopic Mass
248.1488305 g/mol
Topological Polar Surface Area
0Ų
Heavy Atom Count
15
Formal Charge
0
Complexity
108
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
2
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-112646099-A | Preparation method of beta-pinene-isobutene-indene copolymer resin and application of beta-pinene-isobutene-indene copolymer resin in toughening and modifying polypropylene | 2020-12-03 |
| JP-2021172623-A | Nitrogen-containing condensed polycyclic aromatic compounds and methods for producing them | 2020-04-28 |
| WO-2021094416-A1 | 7-pyrimidine-2-yl-oxy-indazole derivatives and their use as herbicides | 2019-11-14 |
| JP-2021046358-A | Regioregular self-doped poly (3,4-ethylenedioxythiophene) derivative and its synthesis method | 2019-09-17 |
| JP-2021046359-A | 2-Hydroxymethyl-2,3-dihydrothieno [3,4-b] [1,4] dioxine-5-carboxylic acid ester | 2019-09-17 |
| JP-2021046361-A | (7-Halo-2,3-dihydrothieno [3,4-b] [1,4] dioxin-2-yl) Methanol | 2019-09-17 |
| WO-2021013693-A1 | Antibody drug conjugates (adcs) with nampt inhibitors | 2019-07-23 |
| JP-2020158411-A | Method for producing condensed ring compound | 2019-03-25 |
| WO-2020170178-A1 | A process for the synthesis anthranilic diamide compounds and intermediates thereof | 2019-02-22 |
| CA-3129950-A1 | A process for the synthesis anthranilic diamide compounds and intermediates thereof | 2019-02-22 |
