Dimethyl maleate

Product Information

Molecular Formula:
C6H8O4
Molecular Weight:
144.13
Description
Dimethyl maleate (CAS# 624-48-6) is a useful research chemical.
Synonyms
dimethyl (Z)-but-2-enedioate
IUPAC Name
dimethyl (Z)-but-2-enedioate
Canonical SMILES
COC(=O)C=CC(=O)OC
InChI
InChI=1S/C6H8O4/c1-9-5(7)3-4-6(8)10-2/h3-4H,1-2H3/b4-3-
InChI Key
LDCRTTXIJACKKU-ARJAWSKDSA-N
Boiling Point
205 °C
Melting Point
-19 °C
Flash Point
103 °C
Purity
> 97.0 % (GC)
Density
1.15 g/cm3
Appearance
Colorless to light yellow clear liquid
Application
Used to make chemicals and polymers; Used to make fine and large scale chemicals.
Refractive Index
1.44
LogP
-0.11140
Vapor Pressure
0.3 [mmHg]

Safety Information

Hazards
H302:
Harmful if swallowed.
H311:
Toxic in contact with skin.
H319:
Causes serious eye irritation.
Precautionary Statement
P260, P261, P264, P270, P271, P272, P280, P301+P312, P301+P330+P331, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P310, P312, P321, P330, P333+P313, P337+P313, P363, P403+P233, P405, and P501
Signal Word
Danger

Computed Properties

XLogP3
0.7
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
4
Rotatable Bond Count
4
Exact Mass
144.04225873 g/mol
Monoisotopic Mass
144.04225873 g/mol
Topological Polar Surface Area
52.6Ų
Heavy Atom Count
10
Formal Charge
0
Complexity
141
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
1
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes

Patents

Publication Number Title Priority Date
CN-113731442-A Dimethyl maleate hydrogenation reaction catalyst, and preparation method and application thereof 2021-08-20
CN-113461523-A Preparation method and equipment of dimethyl succinate 2021-07-06
CN-113292707-A Preparation method of terminal group functionalized hyperbranched polyolefin 2021-06-01
CN-112961058-A Process method for preparing glycol maleate 2021-02-08
CN-112812008-A Method for preparing diacid diester compound under catalysis of deep eutectic solvent 2021-01-11
CN-213286754-U On-line monitoring dimethyl maleate synthesis reaction device 2020-09-27
CN-213286787-U Novel dimethyl maleate neutralizing device 2020-09-27
CN-213286788-U Continuous tower reaction unit of dimethyl maleate 2020-09-27
CN-114196004-A Ternary dual-graft copolymer and preparation method and application thereof 2020-09-18
CN-111848672-A Continuous synthesis process of phosphonic acid tetramethyl succinate 2020-08-26

Literatures

PMID Publication Date Title Journal
21321691 2011-04-07 A novel pH-responsive polysaccharidic ionic complex for proapoptotic D-(KLAKLAK)2 peptide delivery Chemical communications (Cambridge, England)
21105742 2011-01-14 Structure-activity comparison of the cytotoxic properties of diethyl maleate and related molecules: identification of diethyl acetylenedicarboxylate as a thiol cross-linking agent Chemical research in toxicology
20136891 2010-02-01 Sensitization to dimethyl fumarate with multiple concurrent patch test reactions Contact dermatitis
18043806 2007-12-21 Experimental and computational evidence for alpha-lactone intermediates in the addition of aqueous bromine to disodium dimethyl-maleate and -fumarate Organic & biomolecular chemistry
17464401 2007-05-07 Steric and electronic factors influencing recognition by a simple, charge neutral norbornene based anion receptor Organic & biomolecular chemistry
14526912 2003-10-01 Insecticidal compounds against Drosophila melanogaster from Cornus officinalis Sieb. et Zucc Natural product research
12418889 2002-11-13 Highly enantioselective Ag(i)-catalyzed [3 + 2] cycloaddition of azomethine ylides Journal of the American Chemical Society
321785 1977-04-01 Antifungal properties of 2-bromo-3-fluorosuccinic acid esters and related compounds Journal of medicinal chemistry
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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