Dimethyl maleate
Product Information
Molecular Formula
C6H8O4
Molecular Weight
144.13
Description
Dimethyl maleate (CAS# 624-48-6) is a useful research chemical.
Synonyms
dimethyl (Z)-but-2-enedioate
IUPAC Name
dimethyl (Z)-but-2-enedioate
SMILES
COC(=O)C=CC(=O)OC
InChI
InChI=1S/C6H8O4/c1-9-5(7)3-4-6(8)10-2/h3-4H,1-2H3/b4-3-
InChI Key
LDCRTTXIJACKKU-ARJAWSKDSA-N
Boiling Point
205 °C
Melting Point
-19 °C
Flash Point
103 °C
Purity
> 97.0 % (GC)
Density
1.15 g/cm3
Appearance
Colorless to light yellow clear liquid
Application
Used to make chemicals and polymers; Used to make fine and large scale chemicals.
Refractive Index
1.44
LogP
-0.11140
Vapor Pressure
0.3 [mmHg]
Safety Information
Hazards
H302:
Harmful if swallowed.
H311:
Toxic in contact with skin.
H319:
Causes serious eye irritation.
Harmful if swallowed.
H311:
Toxic in contact with skin.
H319:
Causes serious eye irritation.
Precautionary Statement
P260, P261, P264, P270, P271, P272, P280, P301+P312, P301+P330+P331, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P310, P312, P321, P330, P333+P313, P337+P313, P363, P403+P233, P405, and P501
Signal Word
Danger
Computed Properties
XLogP3
0.7
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
4
Rotatable Bond Count
4
Exact Mass
144.04225873 g/mol
Monoisotopic Mass
144.04225873 g/mol
Topological Polar Surface Area
52.6Ų
Heavy Atom Count
10
Formal Charge
0
Complexity
141
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
1
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-113731442-A | Dimethyl maleate hydrogenation reaction catalyst, and preparation method and application thereof | 2021-08-20 |
| CN-113461523-A | Preparation method and equipment of dimethyl succinate | 2021-07-06 |
| CN-113292707-A | Preparation method of terminal group functionalized hyperbranched polyolefin | 2021-06-01 |
| CN-112961058-A | Process method for preparing glycol maleate | 2021-02-08 |
| CN-112812008-A | Method for preparing diacid diester compound under catalysis of deep eutectic solvent | 2021-01-11 |
| CN-213286754-U | On-line monitoring dimethyl maleate synthesis reaction device | 2020-09-27 |
| CN-213286787-U | Novel dimethyl maleate neutralizing device | 2020-09-27 |
| CN-213286788-U | Continuous tower reaction unit of dimethyl maleate | 2020-09-27 |
| CN-114196004-A | Ternary dual-graft copolymer and preparation method and application thereof | 2020-09-18 |
| CN-111848672-A | Continuous synthesis process of phosphonic acid tetramethyl succinate | 2020-08-26 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 21321691 | 2011-04-07 | A novel pH-responsive polysaccharidic ionic complex for proapoptotic D-(KLAKLAK)2 peptide delivery | Chemical communications (Cambridge, England) |
| 21105742 | 2011-01-14 | Structure-activity comparison of the cytotoxic properties of diethyl maleate and related molecules: identification of diethyl acetylenedicarboxylate as a thiol cross-linking agent | Chemical research in toxicology |
| 20136891 | 2010-02-01 | Sensitization to dimethyl fumarate with multiple concurrent patch test reactions | Contact dermatitis |
| 18043806 | 2007-12-21 | Experimental and computational evidence for alpha-lactone intermediates in the addition of aqueous bromine to disodium dimethyl-maleate and -fumarate | Organic & biomolecular chemistry |
| 17464401 | 2007-05-07 | Steric and electronic factors influencing recognition by a simple, charge neutral norbornene based anion receptor | Organic & biomolecular chemistry |
| 14526912 | 2003-10-01 | Insecticidal compounds against Drosophila melanogaster from Cornus officinalis Sieb. et Zucc | Natural product research |
| 12418889 | 2002-11-13 | Highly enantioselective Ag(i)-catalyzed [3 + 2] cycloaddition of azomethine ylides | Journal of the American Chemical Society |
| 321785 | 1977-04-01 | Antifungal properties of 2-bromo-3-fluorosuccinic acid esters and related compounds | Journal of medicinal chemistry |
