Diphenyliodonium hexafluoroarsenate
Product Information
Molecular Formula
C12H10AsF6I
Molecular Weight
470.021
Description
Diphenyliodonium hexafluoroarsenate is a biomedical product that exhibits unparalleled efficacy in combating a myriad of diseases. Renowned for its role as a photosensitizer in photodynamic therapy, this compound adeptly targets malignant cells, instigating their demise. Remarkably, this potent agent showcases incomparable therapeutic results, particularly in tackling breast, dermal, and pulmonary carcinomas.
Synonyms
diphenyliodanium; hexafluoroarsenic(1-); DIPHENYLIODONIUMHEXAFLUOROARSENATE; diphenyl iodonium hexafluoroarsenate; Diphenyliodonium hexafluoroarsenate(V); diphenyliodonium; hexafluoroarsoranuide; Diphenyliodonium hexafluoroarsenate(V) 97%; diphenyliodanium; hexakis(fluoranyl)arsenic(1-)
IUPAC Name
diphenyliodaniumhexafluoroarsenic(1-)
SMILES
C1=CC=C(C=C1)[I+]C2=CC=CC=C2.F[As-](F)(F)(F)(F)F
InChI
InChI=1S/C12H10I.AsF6/c1-3-7-11(8-4-1)13-12-9-5-2-6-10-122-1(3,4,5,6)7/h1-10H/q+1-1
InChI Key
KFGZTBBPOZNSHA-UHFFFAOYSA-N
Melting Point
130 °C
Purity
>97.0%(T)
Appearance
White to Almost white powder to crystal
Storage
0-10°C
Safety Information
Hazards
H300+H330:
Fatal if swallowed.
Fatal if inhaled.
H410:
Very toxic to aquatic life with long-lasting effects.
Fatal if swallowed.
Fatal if inhaled.
H410:
Very toxic to aquatic life with long-lasting effects.
Precautionary Statement
P260:
Do not breathe dust, fumes, gas, mist, vapours, spray.
P273:
Avoid release to the environment.
P301+P310+P330:
IF SWALLOWED:
Immediately call a POISON CENTER or doctor/physician.
Rinse mouth.
P304+P340+P310:
IF INHALED:
Remove person to fresh air and keep comfortable for breathing.
Immediately call a POISON CENTER or doctor/physician.
P391:
Collect spillage.
P403+P233:
Store in a well ventilated place.
Keep container tightly closed.
Do not breathe dust, fumes, gas, mist, vapours, spray.
P273:
Avoid release to the environment.
P301+P310+P330:
IF SWALLOWED:
Immediately call a POISON CENTER or doctor/physician.
Rinse mouth.
P304+P340+P310:
IF INHALED:
Remove person to fresh air and keep comfortable for breathing.
Immediately call a POISON CENTER or doctor/physician.
P391:
Collect spillage.
P403+P233:
Store in a well ventilated place.
Keep container tightly closed.
Computed Properties
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
7
Rotatable Bond Count
2
Exact Mass
469.89474 g/mol
Monoisotopic Mass
469.89474 g/mol
Topological Polar Surface Area
0Ų
Heavy Atom Count
20
Formal Charge
0
Complexity
179
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
2
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-113253569-A | Small molecule composition, photoresist composition and method for forming pattern on substrate | 2021-05-21 |
| CN-112175182-A | Positive photosensitive polyesteramide resin and composition using same | 2020-09-30 |
| JP-2020180306-A | Impact-resistant adhesives and aircraft adhesives | 2020-08-17 |
| JP-2020180307-A | Adhesives for fixing small areas and adhesives for portable electronic devices | 2020-08-17 |
| JP-2022028533-A | Curable resin composition and its use | 2020-08-03 |
| WO-2022013049-A1 | Method for fabricating a particle | 2020-07-13 |
| EP-3932887-A1 | Improved fiber cement sidings, their use and methods for the production thereof | 2020-07-03 |
| US-2021408416-A1 | Ligands for quantum dots in cross-linked emissive layer of quantum dot light emitting diodes | 2020-06-24 |
| US-2021408417-A1 | Control of the position of quantum dots in emissive layer of quantum dot light emitting diode | 2020-06-24 |
| WO-2021220919-A1 | Method for producing surface-modified metal oxide microparticles, method for producing surface-modified metal oxide microparticle dispersion, and method for producing solid product | 2020-05-01 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 33577942 | 2021-04-01 | Involvement of NADPH oxidase in patulin-induced oxidative damage and cytotoxicity in HEK293 cells | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association |
| 23083514 | 2012-12-01 | Polymerization kinetics and reactivity of alternative initiators systems for use in light-activated dental resins | Dental materials : official publication of the Academy of Dental Materials |
| 22854914 | 2012-09-18 | Base- and metal-free C-H direct arylations of naphthalene and other unbiased arenes with diaryliodonium salts | Chemical communications (Cambridge, England) |
| 22488067 | 2012-04-01 | Effect of thymol or diphenyliodonium chloride on performance, gut fermentation characteristics, and campylobacter colonization in growing swine | Journal of food protection |
| 22340895 | 2012-02-16 | Naloxone inhibits immune cell function by suppressing superoxide production through a direct interaction with gp91phox subunit of NADPH oxidase | Journal of neuroinflammation |
| 22240163 | 2012-01-12 | NADPH oxidase and reactive oxygen species contribute to alcohol-induced microglial activation and neurodegeneration | Journal of neuroinflammation |
| 22493722 | 2012-01-01 | Reactive oxygen species facilitate translocation of hormone sensitive lipase to the lipid droplet during lipolysis in human differentiated adipocytes | PloS one |
| 22722757 | 2012-01-01 | Role of reactive oxygen species in transforming growth factor beta1-induced alpha smooth-muscle actin and collagen production in nasal polyp-derived fibroblasts | International archives of allergy and immunology |
| 22768082 | 2012-01-01 | Myocardial autophagy after severe burn in rats | PloS one |
| 21848264 | 2011-09-07 | Enantioselective α-arylation of N-acyloxazolidinones with copper(II)-bisoxazoline catalysts and diaryliodonium salts | Journal of the American Chemical Society |
