Hexamethylenediamine dihydrochloride
Product Information
Molecular Formula
C6H18Cl2N2
Molecular Weight
189.13
Description
An intermediate in the manufacturing of Nylon.
Synonyms
hexane-1,6-diamine;dihydrochloride
IUPAC Name
hexane-1,6-diamine;dihydrochloride
SMILES
C(CCCN)CCN.Cl.Cl
InChI
InChI=1S/C6H16N2.2ClH/c7-5-3-1-2-4-6-8;;/h1-8H2;2*1H
InChI Key
XMVQMBLTFKAIOX-UHFFFAOYSA-N
Boiling Point
205 °C at 760 mmHg
Melting Point
256-257 °C (lit.)
Solubility
H2O
Appearance
White to almost white powder to crystal
LogP
3.46880
Safety Information
Hazards
H315:
Causes skin irritation.
H319:
Causes serious eye irritation.
Causes skin irritation.
H319:
Causes serious eye irritation.
Precautionary Statement
P261, P264, P271, P272, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P333+P313, P337+P313, P362, P363, P403+P233, P405, and P501
Signal Word
Warning
Computed Properties
Hydrogen Bond Donor Count
4
Hydrogen Bond Acceptor Count
2
Rotatable Bond Count
5
Exact Mass
188.0847040 g/mol
Monoisotopic Mass
188.0847040 g/mol
Topological Polar Surface Area
52Ų
Heavy Atom Count
10
Formal Charge
0
Complexity
31.5
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
3
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| US-2020131431-A1 | Chemical additives and surfactant combinations for favorable wettability alteration and improved hydrocarbon recovery factors | 2018-10-26 |
| EP-3682864-A1 | Use of a diamine to improve the mechanical strength of hair, and hair care agent containing same | 2017-09-15 |
| US-2020140626-A1 | Method of preparing a hydrogel product | 2017-06-28 |
| WO-2019002368-A1 | GLYCOSAMINOGLYCANES RETICULATED AND FUNCTIONALIZED | 2017-06-28 |
| WO-2019002372-A1 | PROCESS FOR PREPARING A HYDROGEN PRODUCT | 2017-06-28 |
| US-2019373895-A1 | Branched polymeric biguanide compounds and their uses | 2017-01-03 |
| WO-2018128823-A1 | Branched polymeric biguanide compounds and their uses | 2017-01-03 |
| US-11044912-B2 | Branched polymeric biguanide compounds and their uses | 2017-01-03 |
| EP-3507325-A2 | Compounds, compositons and methods related to antimicrobial applications | 2016-08-31 |
| WO-2018042367-A2 | Compounds, compositons and methods related to antimicrobial applications | 2016-08-31 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 24411478 | 2014-02-01 | Synthesis, in vitro antimalarial activity and cytotoxicity of novel 4-aminoquinolinyl-chalcone amides | Bioorganic & medicinal chemistry |
| 22905948 | 2012-09-26 | Receptor-based detection of 2,4-dinitrotoluene using modified three-dimensionally ordered macroporous carbon electrodes | ACS applied materials & interfaces |
| 21527495 | 2012-08-01 | Improved synthesis of hyaluronic acid hydrogel and its effect on tissue augmentation | Journal of biomaterials applications |
| 21645885 | 2011-09-06 | 1-Deoxy-D-galactonojirimycins with dansyl capped N-substituents as β-galactosidase inhibitors and potential probes for GM1 gangliosidosis affected cell lines | Carbohydrate research |
| 20658209 | 2011-01-01 | Immobilization of phenylalanine dehydrogenase and its application in flow-injection analysis system for determination of plasma phenylalanine | Applied biochemistry and biotechnology |
| 20978689 | 2011-01-01 | Factors affecting variability in the urinary biomarker 1,6-hexamethylene diamine in workers exposed to 1,6-hexamethylene diisocyanate | Journal of environmental monitoring : JEM |
| 21674322 | 2011-01-01 | Enzymatically catalyzed conjugation of a biodegradable polymer to proteins and small molecules using microbial transglutaminase | Methods in molecular biology (Clifton, N.J.) |
| 20530123 | 2010-08-01 | Urine 1,6-hexamethylene diamine (HDA) levels among workers exposed to 1,6-hexamethylene diisocyanate (HDI) | The Annals of occupational hygiene |
| 20445846 | 2010-03-01 | Effect of creatinine and specific gravity normalization on urinary biomarker 1,6-hexamethylene diamine | Journal of environmental monitoring : JEM |
| 20078098 | 2010-02-17 | Effect of cross-linking reagents for hyaluronic acid hydrogel dermal fillers on tissue augmentation and regeneration | Bioconjugate chemistry |
