L(-)-Camphor
Product Information
Molecular Formula
C10H16O
Molecular Weight
152.23
Description
L-camphor appears as colorless or white crystals. Fragrant and penetrating odor. Slightly bitter and cooling taste. Odor index at 68 °F: 40. Flash point 149 °F. Burns with a bright, smoky flame. Sublimes appreciably at room temperature and pressure; 14% sublimes within 60 minutes at 176 °F and 12 mmHg.
Synonyms
(-)-Alcanfor; (1s,4s)-(-)-campho; 7,7-trimethyl-(1s)-bicyclo(2.2.1)heptan-2-on; 7,7-trimethyl-(1s)-bicyclo[2.2.1]heptan-2-on; Camphor, (1S,4S)-(-)-; Camphor, l-, (-)-; CAMPHORE; Levo-(-)-camphor
IUPAC Name
(1S,4S)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one
SMILES
CC1(C2CCC1(C(=O)C2)C)C
InChI
InChI=1S/C10H16O/c1-9(2)7-4-5-10(9,3)8(11)6-7/h7H,4-6H2,1-3H3/t7-,10+/m0/s1
InChI Key
DSSYKIVIOFKYAU-OIBJUYFYSA-N
Boiling Point
204°C
Melting Point
178-180°C
Flash Point
150 °F
Purity
>96.0%(GC)
Density
0.990 g/cm3
Solubility
1 g/800 mL at 77 °F
Appearance
White to off-white solid
Application
Naturally occurring form of camphor; Used in organic synthesis and as an odorant, flavoring agent, moth repellent, preservative, and plasticizer in cosmetics; Also used as a topical analgesic and antipruritic; Used as a plasticizer for cellulose esters and ethers, to make plastics, cymene, and incense, in lacquers, varnishes, explosives, embalming fluids, pyrotechnics, and insect repellents.
Vapor Pressure
1 mmHg at 106.7 °F
Safety Information
Hazards
H228:
Flammable solid.
H302:
Harmful if swallowed.
H315:
Causes skin irritation.
H319:
Causes serious eye irritation.
Flammable solid.
H302:
Harmful if swallowed.
H315:
Causes skin irritation.
H319:
Causes serious eye irritation.
Precautionary Statement
P210:
Keep away from heat, sparks, open flames, hot surfaces. No smoking.
P264:
Wash thoroughly after handling.
P280:
Wear protective gloves/protective clothing/eye protection/face protection.
P337+P313:
If eye irritation persists:
Get medical advice/attention.
P370+P378:
In case of fire:
Use for extinction:
P501:
Dispose of contents/container in accordance with local/regional/national/international regulations.
Keep away from heat, sparks, open flames, hot surfaces. No smoking.
P264:
Wash thoroughly after handling.
P280:
Wear protective gloves/protective clothing/eye protection/face protection.
P337+P313:
If eye irritation persists:
Get medical advice/attention.
P370+P378:
In case of fire:
Use for extinction:
P501:
Dispose of contents/container in accordance with local/regional/national/international regulations.
Computed Properties
XLogP3
2.2
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
1
Rotatable Bond Count
0
Exact Mass
152.120115130 g/mol
Monoisotopic Mass
152.120115130 g/mol
Topological Polar Surface Area
17.1Ų
Heavy Atom Count
11
Formal Charge
0
Complexity
217
Isotope Atom Count
0
Defined Atom Stereocenter Count
2
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-113693962-A | Fibronectin-containing multiple protein repair composition and preparation method thereof | 2021-08-09 |
| CN-112716829-A | Brightening and whitening composition | 2021-02-23 |
| JP-2021075562-A | Cosmetics | 2021-02-10 |
| CN-112741773-A | Active matter wrapping method | 2021-02-07 |
| CN-112754978-A | Moisturizing, relieving and repairing composition | 2021-02-03 |
| CN-112932996-A | Whitening composition and essence thereof | 2021-02-03 |
| CN-112662639-A | Short-chain alcohol dehydrogenase and application thereof | 2021-01-21 |
| WO-2022029579-A1 | Emulsifier composition for personal care formulation | 2020-08-05 |
| JP-2022021339-A | A resin composition for forming an odor substance receiving layer, a sensor element using the resin composition, an odor sensor, and an odor measuring device. | 2020-07-21 |
| JP-2022021340-A | A resin composition for forming an odor substance receiving layer, a sensor element using the resin composition, an odor sensor, and an odor measuring device. | 2020-07-21 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 23828908 | 2013-09-01 | Camphor activates and sensitizes transient receptor potential melastatin 8 (TRPM8) to cooling and icilin | Chemical senses |
| 23625413 | 2013-05-01 | Camphor modulates TRPV3 cation channels activity by interacting with critical pore-region cysteine residues | Pakistan journal of pharmaceutical sciences |
| 17268056 | 2007-02-01 | In vitro metabolism of (-)-camphor using human liver microsomes and CYP2A6 | Biological & pharmaceutical bulletin |
| 16939314 | 2006-09-06 | Chemical composition and antifungal activity of Salvia macrochlamys and Salvia recognita essential oils | Journal of agricultural and food chemistry |
| 16192383 | 2005-09-28 | Camphor activates and strongly desensitizes the transient receptor potential vanilloid subtype 1 channel in a vanilloid-independent mechanism | The Journal of neuroscience : the official journal of the Society for Neuroscience |
