Metformin EP Impurity C
Product Information
Molecular Formula
C5H10N6
Molecular Weight
154.17
Description
Metformin EP Impurity C is an impurity of Metformin (HCl), an oral hypoglycemic agent that slows electron transport in the oxidation pathway in mitochondria.
Synonyms
Metformin USP Related Compound C; 2,4-Diamino-6-(dimethylamino)-s-triazine; 2-(Dimethylamino)-4,6-diamino-s-triazine; 2,4-Diamino-6-dimethylamino-1,3,5-triazine; N,N-Dimethyl-1,3,5-triazine-2,4,6-triamine; N2,N2-Dimethylmelamine
IUPAC Name
2-N,2-N-dimethyl-1,3,5-triazine-2,4,6-triamine
SMILES
CN(C)C1=NC(=NC(=N1)N)N
InChI
InChI=1S/C5H10N6/c1-11(2)5-9-3(6)8-4(7)10-5/h1-2H3,(H4,6,7,8,9,10)
InChI Key
IEFWDQQGFDLKFK-UHFFFAOYSA-N
Boiling Point
414.8±28.0 °C at 760 mmHg
Melting Point
>300 °C (dec.)
Purity
≥95%
Density
1.380±0.06 g/cm3
Solubility
Soluble in Aqueous Acid (Slightly), DMSO (Slightly), Methanol (Very Slightly, Heated)
Appearance
White to Off-White Solid
Storage
Store at 2-8 °C
Related CAS
2827-50-1 (monohydrochloride) 16274-63-8 (x-hydrochloride)
Safety Information
Hazards
H315:
Causes skin irritation.
H319:
Causes serious eye irritation.
Causes skin irritation.
H319:
Causes serious eye irritation.
Precautionary Statement
P264:
Wash thoroughly after handling.
P280:
Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:
IF ON SKIN:
Wash with plenty of soap and water.
P332+P313:
If skin irritation occurs:
Get medical advice/attention.
P337+P313:
If eye irritation persists:
Get medical advice/attention.
P362+P364:
Take off contaminated clothing. [As modified by IV ATP].
And wash it before reuse. [Added by IV ATP].
Wash thoroughly after handling.
P280:
Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:
IF ON SKIN:
Wash with plenty of soap and water.
P332+P313:
If skin irritation occurs:
Get medical advice/attention.
P337+P313:
If eye irritation persists:
Get medical advice/attention.
P362+P364:
Take off contaminated clothing. [As modified by IV ATP].
And wash it before reuse. [Added by IV ATP].
Computed Properties
XLogP3
0.4
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
6
Rotatable Bond Count
1
Exact Mass
154.09669434 g/mol
Monoisotopic Mass
154.09669434 g/mol
Topological Polar Surface Area
94Ų
Heavy Atom Count
11
Formal Charge
0
Complexity
116
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-112058102-A | High-rejection-rate ultrafiltration membrane and preparation method thereof | 2020-09-07 |
| CN-112011267-A | Heat-preservation and heat-insulation coating and preparation method thereof | 2020-09-07 |
| CN-112011267-B | Heat-preservation and heat-insulation coating and preparation method thereof | 2020-09-07 |
| WO-2021161989-A1 | Liquid crystal aligning agent, liquid crystal alignment film, liquid crystal display device, and diamine | 2020-02-14 |
| CN-110577644-A | preparation method of triazine polyimide capable of being coated | 2019-09-17 |
| WO-2020203110-A1 | Liquid crystal aligning agent, liquid crystal alignment film, liquid crystal display element, and diamine | 2019-03-29 |
| TW-202104559-A | Liquid crystal alignment agent, liquid crystal alignment film, liquid crystal display element and diamine | 2019-03-29 |
| CN-113711117-A | Liquid crystal aligning agent, liquid crystal alignment film, liquid crystal display element, and diamine | 2019-03-29 |
| KR-20210145744-A | Liquid crystal aligning agent, liquid crystal aligning film, liquid crystal display element and diamine | 2019-03-29 |
| TW-202045697-A | Liquid crystal alignment agent, liquid crystal alignment film and liquid crystal display element using the same | 2019-02-27 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 15134404 | 2004-01-01 | [Occupational allergic contact dermatitis caused by dimethylmelamine resin in a textile worker] | Giornale italiano di medicina del lavoro ed ergonomia |
