Nickel Diethyldithiocarbamate
Product Information
Molecular Formula
C10H20N2NiS4
Molecular Weight
355.22
Description
Nickel diethyldithiocarbamate is a potent antitumor agent in biomedicine that demonstrates remarkable efficacy against diverse cancer types such as lung, breast, and prostate cancer. Research studies have substantiated its capability to impede tumor proliferation and trigger programmed cell death in malignant cells. Moreover, notable findings indicate its potential to suppress angiogenesis, a pivotal event in tumor advancement. The multifaceted pharmacological activities of this compound position it as a promising therapeutic candidate for cancer treatment.
Synonyms
Diethyldithiocarbamic Acid Nickel Salt
IUPAC Name
N,N-diethylcarbamodithioatenickel(2+)
SMILES
CCN(CC)C(=S)[S-].CCN(CC)C(=S)[S-].[Ni+2]
InChI
InChI=1S/2C5H11NS2.Ni/c2*1-3-6(4-2)5(7)8/h2*3-4H2,1-2H3,(H,7,8)/q+2/p-2
InChI Key
NCLUCMXMAPDFGT-UHFFFAOYSA-L
Purity
>97.0%(T)
Appearance
Green to Dark green powder to crystal
Safety Information
Hazards
H317:
May cause an allergic skin reaction.
H334:
May cause allergy or asthma symptoms or breathing difficulties if inhaled.
H350:
May cause cancer.
H372:
Causes damage to organs through prolonged or repeated exposure.
May cause an allergic skin reaction.
H334:
May cause allergy or asthma symptoms or breathing difficulties if inhaled.
H350:
May cause cancer.
H372:
Causes damage to organs through prolonged or repeated exposure.
Precautionary Statement
P201:
Obtain special instructions before use.
P260:
Do not breathe dust, fumes, gas, mist, vapours, spray.
P280:
Wear protective gloves/protective clothing/eye protection/face protection.
P284:
[In case of inadequate ventilation] wear respiratory protection. [As modified by IV ATP].
P304+P340:
IF INHALED:
Remove person to fresh air and keep comfortable for breathing.
P308+P313:
If exposed or concerned:
Get medical advice/attention.
Obtain special instructions before use.
P260:
Do not breathe dust, fumes, gas, mist, vapours, spray.
P280:
Wear protective gloves/protective clothing/eye protection/face protection.
P284:
[In case of inadequate ventilation] wear respiratory protection. [As modified by IV ATP].
P304+P340:
IF INHALED:
Remove person to fresh air and keep comfortable for breathing.
P308+P313:
If exposed or concerned:
Get medical advice/attention.
Computed Properties
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
4
Rotatable Bond Count
4
Exact Mass
353.986275 g/mol
Monoisotopic Mass
353.986275 g/mol
Topological Polar Surface Area
72.7Ų
Heavy Atom Count
17
Formal Charge
0
Complexity
73
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
3
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-113463075-A | Chemical copper plating solution and preparation method thereof | 2021-06-04 |
| CN-113463074-A | Copper deposition composition and copper deposition method | 2021-06-03 |
| WO-2022035639-A1 | Production of thiopolymers by reactive extrusion | 2020-08-14 |
| CN-113589665-A | Developing roller | 2020-05-01 |
| JP-2021175997-A | Develop roller | 2020-05-01 |
| WO-2021202659-A1 | Metal-based catalyst for producing polydienes | 2020-03-31 |
| CN-111403607-A | Chelated perovskite material, film, device and preparation method and application thereof | 2020-03-25 |
| WO-2021192897-A1 | Acrylic rubber composition and rubber crosslinked product | 2020-03-25 |
| CN-113391531-A | Conductive roller for electrophotography | 2020-03-13 |
| JP-2021144198-A | Conductive roller for electrophotographic | 2020-03-13 |
