PAMAM Dendrimer G2-OH
Product Information
Molecular Formula
C142H288N58O28
Molecular Weight
3256.18
Description
PAMAM Dendrimer G2-OH is a 20 wt. % solution of second-generation Starburst polyamidoamine (PAMAM) dendrimer in methyl alcohol. The solution is primarily used in biomedicine for drug delivery systems, biomedical imaging, and targeted therapy due to its ability to encapsulate and deliver various drugs. It finds applications in the drug development of diseases such as cancer, viral infections, and neurological disorders.
Synonyms
PAMAM-G2-OH; 2-Propenoic acid, methyl ester, polymer with 1,2-ethanediamine; 1,2-Ethanediamine, polymer with methyl 2-propenoate; Acrylic acid methyl ester, polymer with ethylenediamine; Ethylenediamine, polymer with methyl acrylate; 1,2-Diaminoethane-methyl acrylate copolymer; 1,2-Ethylenediamine-methyl acrylate copolymer; CYD 110C; CYD 130A; CYD 150A; CYD-WU 438; Ethylenediamine-methyl acrylate copolymer; Ethylenediaminemethyl acrylate polymer; G2 PAMAM; G3 PAMAM; Methyl acrylate-ethylenediamine copolymer; PAMAM; PAMAM G 4.5; PAMAM starburst G-2; PAMAM-G 2; PAMAM-G 3; PAMAM-G 4; PAMAM-G 5; PAMAM-G 6; PAMAM-G 7; PAMAM-G 8; Polyamidoaminedimethyl maleic anhydide copolymer; Starburst 2nd Generation; Starburst Dendrimer Generation 2; Starburst Generation 2; PAMAM dendrimer, ethylenediamine core, generation 2.0 solution; pamam dendrimer, generation 2 solution; STARBURST (PAMAM) DENDRIMER, GENERATION 2, 20 WT. % SOLUTION IN METHYL ALCOHOL
IUPAC Name
N-(2-aminoethyl)-3-[[3-(2-aminoethylamino)-3-oxopropyl]-[2-[3-[[3-[2-[bis[3-(2-aminoethylamino)-3-oxopropyl]amino]ethylamino]-3-oxopropyl]-[2-[3-[[3-[2-[bis[3-[2-[bis[3-(2-aminoethylamino)-3-oxopropyl]amino]ethylamino]-3-oxopropyl]amino]ethylamino]-3-oxopropyl]-[2-[bis[3-[2-[bis[3-[2-[bis[3-(2-aminoethylamino)-3-oxopropyl]amino]ethylamino]-3-oxopropyl]amino]ethylamino]-3-oxopropyl]amino]ethyl]amino]propanoylamino]ethyl]amino]propanoylamino]ethyl]amino]propanamide
SMILES
C(CN(CCC(=O)NCCN)CCNC(=O)CCN(CCC(=O)NCCN(CCC(=O)NCCN)CCC(=O)NCCN)CCNC(=O)CCN(CCC(=O)NCCN(CCC(=O)NCCN(CCC(=O)NCCN)CCC(=O)NCCN)CCC(=O)NCCN(CCC(=O)NCCN)CCC(=O)NCCN)CCN(CCC(=O)NCCN(CCC(=O)NCCN(CCC(=O)NCCN)CCC(=O)NCCN)CCC(=O)NCCN(CCC(=O)NCCN)CCC(=O)NCCN)CCC(=O)NCCN(CCC(=O)NCCN(CCC(=O)NCCN)CCC(=O)NCCN)CCC(=O)NCCN(CCC(=O)NCCN)CCC(=O)NCCN)C(=O)NCCN
InChI
InChI=1S/C142H288N58O28/c143-29-45-159-115(201)1-73-187(74-2-116(202)160-46-30-144)101-61-175-131(217)17-89-195(90-18-132(218)176-62-102-188(75-3-117(203)161-47-31-145)76-4-118(204)162-48-32-146)109-69-183-139(225)25-97-199(98-26-140(226)184-70-110-196(91-19-133(219)177-63-103-189(77-5-119(205)163-49-33-147)78-6-120(206)164-50-34-148)92-20-134(220)178-64-104-190(79-7-121(207)165-51-35-149)80-8-122(208)166-52-36-150)113-114-200(99-27-141(227)185-71-111-197(93-21-135(221)179-65-105-191(81-9-123(209)167-53-37-151)82-10-124(210)168-54-38-152)94-22-136(222)180-66-106-192(83-11-125(211)169-55-39-153)84-12-126(212)170-56-40-154)100-28-142(228)186-72-112-198(95-23-137(223)181-67-107-193(85-13-127(213)171-57-41-155)86-14-128(214)172-58-42-156)96-24-138(224)182-68-108-194(87-15-129(215)173-59-43-157)88-16-130(216)174-60-44-158/h1-114,143-158H2,(H,159,201)(H,160,202)(H,161,203)(H,162,204)(H,163,205)(H,164,206)(H,165,207)(H,166,208)(H,167,209)(H,168,210)(H,169,211)(H,170,212)(H,171,213)(H,172,214)(H,173,215)(H,174,216)(H,175,217)(H,176,218)(H,177,219)(H,178,220)(H,179,221)(H,180,222)(H,181,223)(H,182,224)(H,183,225)(H,184,226)(H,185,227)(H,186,228)
InChI Key
QYMWEDAKQRTCGD-UHFFFAOYSA-N
Flash Point
49.5 °F
Density
0.86 g/mL at 25 °C
Storage
Store at 2-8 °C
Refractive Index
n20/D 1.362
Related CAS
93376-66-0 (Deleted CAS)
Safety Information
Hazards
H225 - H301 + H311 + H331 - H370
Precautionary Statement
P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
Computed Properties
XLogP3
-35.3
Hydrogen Bond Donor Count
44
Hydrogen Bond Acceptor Count
58
Rotatable Bond Count
155
Exact Mass
3255.2928656 g/mol
Monoisotopic Mass
3254.2895108 g/mol
Topological Polar Surface Area
1280Ų
Heavy Atom Count
228
Formal Charge
0
Complexity
4950
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes