Tributyl phosphite

Product Information

Molecular Formula:
C12H27O3P
Molecular Weight:
250.31
Description
Tributyl phosphite is an indispensable chemical compound of paramount significance and emerges as an irreplaceable catalyst and stabilizer within the biomedical realm. Its multifaceted utility resonates profoundly in myriad pharmaceutical formulations, particularly within the expanse of leukemia treatments and various other medicinal concoctions. Remarkably, Tributyl phosphite assumes a pivotal mantle in advancing the frontiers of organic phosphorus compounds, strategically enmeshing with the pursuit of combatting diverse maladies.
Synonyms
TRIBUTYLPHOSPHITE; 102-85-2; Tributoxyphosphine; Tri-n-butylphosphite; Phosphorousacid,tributylester; Tributylfosfit
IUPAC Name
tributyl phosphite
Canonical SMILES
CCCCOP(OCCCC)OCCCC
InChI
InChI=1S/C12H27O3P/c1-4-7-10-13-16(14-11-8-5-2)15-12-9-6-3/h4-12H2,1-3H3
InChI Key
XTTGYFREQJCEML-UHFFFAOYSA-N
Boiling Point
125-128°C(10 torr)
Melting Point
-80°C
Flash Point
129 °C
Purity
95%
Density
0.915
Appearance
Clear colorless liquid
Refractive Index
1.43

Safety Information

Hazards
H312:
Harmful in contact with skin.
H315:
Causes skin irritation.
H319:
Causes serious eye irritation.
Precautionary Statement
P264:
Wash thoroughly after handling.
P280:
Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352+P312:
IF ON SKIN:
Wash with plenty of soap and water.
Call a POISON CENTER or doctor/physician if you feel unwell.
P332+P313:
If skin irritation occurs:
Get medical advice/attention.
P337+P313:
If eye irritation persists:
Get medical advice/attention.
P501:
Dispose of contents/container in accordance with local/regional/national/international regulations.

Computed Properties

XLogP3
3.8
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
3
Rotatable Bond Count
12
Exact Mass
250.16978172 g/mol
Monoisotopic Mass
250.16978172 g/mol
Topological Polar Surface Area
27.7Ų
Heavy Atom Count
16
Formal Charge
0
Complexity
110
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes

Patents

Publication Number Title Priority Date
CN-114058189-A Addition type flame-retardant high-temperature-resistant silicon rubber and preparation method and application thereof 2021-12-31
CN-114057789-A Preparation method of aryl phosphate 2021-12-09
CN-114058138-A Super wear-resistant PVC material for conveying belt 2021-12-07
CN-114032019-A Preparation method of high-weather-resistance wear-resistant coating for surface of PC (polycarbonate) plate 2021-12-03
CN-113980266-A Low-yellow-index long-carbon-chain polyamide and preparation method thereof 2021-11-30
CN-114031823-A Novel rubber protective floor mat and preparation method thereof 2021-11-15
CN-113972415-A Heat pipe containing phosphorus flame retardant for high-capacity battery 2021-10-29
CN-113999261-A O-dimethyl aromatic ring diphosphino ligand compound and synthetic method thereof 2021-10-26
CN-114188159-A Capacitor working electrolyte for high-fidelity audio and preparation method thereof 2021-10-13
CN-113908470-A Heat pipe containing gas production device for battery and fire extinguishing method thereof 2021-09-30

Literatures

PMID Publication Date Title Journal
15323502 2004-08-31 Reaction of tributyl phosphite with oxidized iron: surface and tribological chemistry Langmuir : the ACS journal of surfaces and colloids
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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