Tributyl phosphite
Product Information
Molecular Formula
C12H27O3P
Molecular Weight
250.31
Description
Tributyl phosphite is an indispensable chemical compound of paramount significance and emerges as an irreplaceable catalyst and stabilizer within the biomedical realm. Its multifaceted utility resonates profoundly in myriad pharmaceutical formulations, particularly within the expanse of leukemia treatments and various other medicinal concoctions. Remarkably, Tributyl phosphite assumes a pivotal mantle in advancing the frontiers of organic phosphorus compounds, strategically enmeshing with the pursuit of combatting diverse maladies.
Synonyms
TRIBUTYLPHOSPHITE; 102-85-2; Tributoxyphosphine; Tri-n-butylphosphite; Phosphorousacid,tributylester; Tributylfosfit
IUPAC Name
tributyl phosphite
SMILES
CCCCOP(OCCCC)OCCCC
InChI
InChI=1S/C12H27O3P/c1-4-7-10-13-16(14-11-8-5-2)15-12-9-6-3/h4-12H2,1-3H3
InChI Key
XTTGYFREQJCEML-UHFFFAOYSA-N
Boiling Point
125-128°C(10 torr)
Melting Point
-80°C
Flash Point
129 °C
Purity
95%
Density
0.915
Appearance
Clear colorless liquid
Refractive Index
1.43
Safety Information
Hazards
H312:
Harmful in contact with skin.
H315:
Causes skin irritation.
H319:
Causes serious eye irritation.
Harmful in contact with skin.
H315:
Causes skin irritation.
H319:
Causes serious eye irritation.
Precautionary Statement
P264:
Wash thoroughly after handling.
P280:
Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352+P312:
IF ON SKIN:
Wash with plenty of soap and water.
Call a POISON CENTER or doctor/physician if you feel unwell.
P332+P313:
If skin irritation occurs:
Get medical advice/attention.
P337+P313:
If eye irritation persists:
Get medical advice/attention.
P501:
Dispose of contents/container in accordance with local/regional/national/international regulations.
Wash thoroughly after handling.
P280:
Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352+P312:
IF ON SKIN:
Wash with plenty of soap and water.
Call a POISON CENTER or doctor/physician if you feel unwell.
P332+P313:
If skin irritation occurs:
Get medical advice/attention.
P337+P313:
If eye irritation persists:
Get medical advice/attention.
P501:
Dispose of contents/container in accordance with local/regional/national/international regulations.
Computed Properties
XLogP3
3.8
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
3
Rotatable Bond Count
12
Exact Mass
250.16978172 g/mol
Monoisotopic Mass
250.16978172 g/mol
Topological Polar Surface Area
27.7Ų
Heavy Atom Count
16
Formal Charge
0
Complexity
110
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-114058189-A | Addition type flame-retardant high-temperature-resistant silicon rubber and preparation method and application thereof | 2021-12-31 |
| CN-114057789-A | Preparation method of aryl phosphate | 2021-12-09 |
| CN-114058138-A | Super wear-resistant PVC material for conveying belt | 2021-12-07 |
| CN-114032019-A | Preparation method of high-weather-resistance wear-resistant coating for surface of PC (polycarbonate) plate | 2021-12-03 |
| CN-113980266-A | Low-yellow-index long-carbon-chain polyamide and preparation method thereof | 2021-11-30 |
| CN-114031823-A | Novel rubber protective floor mat and preparation method thereof | 2021-11-15 |
| CN-113972415-A | Heat pipe containing phosphorus flame retardant for high-capacity battery | 2021-10-29 |
| CN-113999261-A | O-dimethyl aromatic ring diphosphino ligand compound and synthetic method thereof | 2021-10-26 |
| CN-114188159-A | Capacitor working electrolyte for high-fidelity audio and preparation method thereof | 2021-10-13 |
| CN-113908470-A | Heat pipe containing gas production device for battery and fire extinguishing method thereof | 2021-09-30 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 15323502 | 2004-08-31 | Reaction of tributyl phosphite with oxidized iron: surface and tribological chemistry | Langmuir : the ACS journal of surfaces and colloids |
