Tributyrin
| Catalog Number | Size | Price | Stock | Quantity |
|---|---|---|---|---|
| BPM-293891 | 5 kg | $420 | In stock |
Product Information
Molecular Formula
C15H26O6
Molecular Weight
302.36
Description
Tributyrin is a triglyceride existing in butter. Tributyrin is a prodrug of butyric acid to enhance antiproliferative effects of dihydroxycholecalciferol in human colon cancer cells, and it is used to identify the bacterium Moraxella catarrhalis in microbiological laboratories.
Synonyms
Glycerol tributyrate; Glyceryl tributyrate; Propane-1,2,3-triyl tributyrate; Butyrin; Butyryl triglyceride
IUPAC Name
2,3-di(butanoyloxy)propyl butanoate
SMILES
CCCC(=O)OCC(COC(=O)CCC)OC(=O)CCC
InChI
InChI=1S/C15H26O6/c1-4-7-13(16)19-10-12(21-15(18)9-6-3)11-20-14(17)8-5-2/h12H,4-11H2,1-3H3
InChI Key
UYXTWWCETRIEDR-UHFFFAOYSA-N
Boiling Point
190 °C / 15 mmHg
Melting Point
-75 °C
Flash Point
180 °C
Purity
95%
Density
1.04 g/cm3
Solubility
Sol in acetone, Benzene
Appearance
Colorless to yellow liquid
Refractive Index
1.44
LogP
2.38490
Vapor Pressure
1.3X10-3 mm Hg at 25 °C
Henry's Law Constant
9.6X10-9 atm cu m/mole at 25 °C /Estimated/
Decomposition
When heated to decomposition it emits acrid smoke and fumes
Odor
FRUITY, BUTTERY
Computed Properties
XLogP3
2.4
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
6
Rotatable Bond Count
14
Exact Mass
302.17293854 g/mol
Monoisotopic Mass
302.17293854 g/mol
Topological Polar Surface Area
78.9Ų
Heavy Atom Count
21
Formal Charge
0
Complexity
304
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-114181874-A | Deep-sea micro bacillus and application thereof in enhancing flavor of aquatic seasoning | 2022-02-16 |
| CN-114181922-A | Recombinant esterase, gene, recombinant bacterium and application of recombinant esterase to degradation of phthalate | 2021-12-10 |
| CN-114041542-A | Feed additive for promoting piglet gastrointestinal health and preparation method thereof | 2021-12-08 |
| CN-113913347-A | Paenibacillus balun TZ-1 and application thereof | 2021-11-24 |
| CN-114027414-A | Traditional Chinese medicine esterase composition for laying hens and application thereof | 2021-11-20 |
| CN-114027097-A | Mushroom culture medium containing nut green seedcase and preparation method thereof | 2021-11-19 |
| CN-113843549-A | Silver soldering paste sintering aid and preparation method and application thereof | 2021-11-18 |
| CN-114107250-A | Lipase CALBgold and preparation method and application thereof | 2021-11-18 |
| CN-114081990-A | Traditional Chinese medicine composite temperature-sensitive gel embolic agent as well as preparation method and application thereof | 2021-11-17 |
| CN-113999793-A | Lactobacillus plantarum with good fermentation characteristics and fragrance production function and screening method thereof | 2021-11-12 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 30503584 | 2019-01-15 | Enhancement of mouse contact hypersensitivity appears with a short chain triacylglycerol but not with a long chain one | Toxicology |
| 29198882 | 2018-03-01 | Adjuvant effect of short chain triacylglycerol tributyrin on a mouse contact hypersensitivity model | Toxicology letters |
| 21940155 | 2012-08-01 | Chemopreventive effects of the dietary histone deacetylase inhibitor tributyrin alone or in combination with vitamin A during the promotion phase of rat hepatocarcinogenesis | The Journal of nutritional biochemistry |
| 22621868 | 2012-07-15 | Tributyrin attenuates obesity-associated inflammation and insulin resistance in high-fat-fed mice | American journal of physiology. Endocrinology and metabolism |
| 22362134 | 2012-06-01 | Modulation of histone deacetylase attenuates naloxone-precipitated opioid withdrawal syndrome | Naunyn-Schmiedeberg's archives of pharmacology |
| 22405988 | 2012-05-30 | Dual function of tributyrin emulsion: solubilization and enhancement of anticancer effect of celecoxib | International journal of pharmaceutics |
| 22426713 | 2012-01-01 | High-throughput screening method for lipases/esterases | Methods in molecular biology (Clifton, N.J.) |
| 22426724 | 2012-01-01 | Purification, biochemical and kinetic properties of recombinant Staphylococcus aureus lipase | Methods in molecular biology (Clifton, N.J.) |
| 22426727 | 2012-01-01 | Molecular modeling of lipase binding to a substrate-water interface | Methods in molecular biology (Clifton, N.J.) |
| 22082136 | 2011-12-14 | Enzymatically catalyzed synthesis of low-calorie structured lipid in a solvent-free system: optimization by response surface methodology | Journal of agricultural and food chemistry |
