2-Morpholinopyrimidin-5-ylboronic acid
Product Information
Molecular Formula
C8H12BN3O3
Molecular Weight
209.01
Description
2-Morpholinopyrimidin-5-ylboronic acid is a vital compound used in the biomedical industry. It exhibits potential as a pharmaceutical intermediate in the development of drugs for treating various diseases. With its unique structural features, it can be utilized in the synthesis of novel therapeutic agents targeting specific diseases.
Synonyms
2-morpholinopyrimidin-5-ylboronic acid; [2-(4-Morpholinyl)-5-pyrimidinyl]boronic acid; 2-Morpholinopyrimidine-5-boronic acid
IUPAC Name
(2-morpholin-4-ylpyrimidin-5-yl)boronic acid
SMILES
B(C1=CN=C(N=C1)N2CCOCC2)(O)O
InChI
InChI=1S/C8H12BN3O3/c13-9(14)7-5-10-8(11-6-7)12-1-3-15-4-2-12/h5-6,13-14H,1-4H2
InChI Key
KFYQOIHLZBDFBU-UHFFFAOYSA-N
Boiling Point
484°C at 760 mmHg
Flash Point
Not applicable
Purity
98%
Density
1.37
Safety Information
Hazards
H302
Computed Properties
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
6
Rotatable Bond Count
2
Exact Mass
209.0971714 g/mol
Monoisotopic Mass
209.0971714 g/mol
Topological Polar Surface Area
78.7Ų
Heavy Atom Count
15
Formal Charge
0
Complexity
194
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| WO-2022007882-A1 | Atx inhibitor, and preparation method therefor and use thereof | 2020-07-09 |
| WO-2020254572-A1 | Egfr inhibitors for the treatment of cancer | 2019-06-21 |
| CN-113993872-A | EGFR inhibitors for the treatment of cancer | 2019-06-21 |
| US-10647712-B2 | Dihydroisoquinoline compound | 2017-01-13 |
| US-2019389855-A1 | Dihydroisoquinoline compound | 2017-01-13 |
| US-2020207755-A1 | Dihydroisoquinoline compound | 2017-01-13 |
| WO-2018130152-A1 | Dihydroisoquinoline compound | 2017-01-13 |
| US-10717730-B1 | Dihydroisoquinoline compound | 2017-01-13 |
| CN-110177785-B | Dihydroisoquinoline compound | 2017-01-13 |
| AU-2017226004-A1 | Inhibitors of WDR5 protein-protein binding | 2016-03-01 |
