1,3,5-Triaza-7-phosphaadamantane,min.97%
Product Information
Molecular Formula
C6H12N3P
Description
1,3,5-Triaza-7-phosphaadamantane min.97% is a useful organic synthesis reagent in the biomedical field. It's extensively applied in manufacturing various antifungal and antiviral drugs.
Synonyms
1,3,5-Triaza-7-phosphaadamantane,min.97%; 1,3,5-TRIAZA-7-PHOSPHAADAMANTANE, MIN. 97%; 1,3,5-Triaza-7-phosphaadamantane; 1,3,5-Triaza-7-phosphatricyclo[3.3.1.13.7]decane, NSC 266642, PTA; 1,3,5-Triaza-7-phosphatricyclo[3.3.1.13,7]decane; 1,3,5-Triaza-9-phos
IUPAC Name
1,3,5-triaza-7-phosphatricyclo[3.3.1.13,7]decane
SMILES
C1N2CN3CN1CP(C2)C3
InChI
InChI=1S/C6H12N3P/c1-7-2-9-3-8(1)5-10(4-7)6-9/h1-6H2
InChI Key
FXXRPTKTLVHPAR-UHFFFAOYSA-N
Boiling Point
232.5°C at 760mmHg
Melting Point
244-250°C
Flash Point
Not applicable
Purity
95%
Computed Properties
XLogP3
0
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
3
Rotatable Bond Count
0
Exact Mass
157.07688439 g/mol
Monoisotopic Mass
157.07688439 g/mol
Topological Polar Surface Area
9.7Ų
Heavy Atom Count
10
Formal Charge
0
Complexity
123
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-113224313-A | Metal organic phosphine frame glass modified metal negative current collector and preparation method thereof | 2021-04-30 |
| ES-2891137-A1 | RUTHENIUM COMPLEXES | 2020-07-13 |
| WO-2022013467-A1 | Ruthenium complexes | 2020-07-13 |
| US-2021403500-A1 | Nucleosides and nucleotides with 3' acetal blocking group | 2020-06-22 |
| JP-6798740-B1 | Tube-shaped iron oxide particles, their manufacturing method, and antibacterial red pigment | 2020-04-14 |
| WO-2021210212-A1 | Tubular iron oxide particles, method for producing same, and antibacterial red pigment | 2020-04-14 |
| JP-2021169378-A | Tube-shaped iron oxide particles, their manufacturing method, and antibacterial red pigment | 2020-04-14 |
| US-11142539-B2 | Phosphinogold(I) complexes and methods of treating cancer | 2020-03-10 |
| US-2021284674-A1 | Phosphinogold(i) complexes and methods of treating cancer | 2020-03-10 |
| CN-111038056-A | Environment-friendly tent material and preparation method thereof | 2019-12-30 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 22513391 | 2012-07-15 | Long-chain cationic derivatives of PTA (1,3,5-triaza-7-phosphaadamantane) as new components of potential non-viral vectors | International journal of pharmaceutics |
| 22506276 | 2012-06-28 | Cellular delivery of pyrenyl-arene ruthenium complexes by a water-soluble arene ruthenium metalla-cage | Dalton transactions (Cambridge, England : 2003) |
| 21904768 | 2011-11-07 | Thiolato gold(I) complexes containing water-soluble phosphane ligands: a characterization of their chemical and biological properties | Dalton transactions (Cambridge, England : 2003) |
| 21999582 | 2011-11-07 | Synthesis, antimicrobial and antiproliferative activity of novel silver(I) tris(pyrazolyl)methanesulfonate and 1,3,5-triaza-7-phosphadamantane complexes | Inorganic chemistry |
| 21788930 | 2011-07-25 | The Suzuki reaction in aqueous media promoted by P, N ligands | Molecules (Basel, Switzerland) |
| 21534534 | 2011-06-09 | Organometallic ruthenium(II) arene compounds with antiangiogenic activity | Journal of medicinal chemistry |
| 20864176 | 2011-03-01 | Synthesis, structures and in vitro cytotoxicity of some cationic cis-platinum(II) complexes containing chelating thiocarbamates | Journal of inorganic biochemistry |
| 21226474 | 2011-02-07 | Water-soluble Cp ruthenium complex containing 1,3,5-triaza-7-phosphaadamantane and 8-thiotheophylline derivatives: synthesis, characterization, and antiproliferative activity | Inorganic chemistry |
| 21194623 | 2011-02-01 | In vitro antitumour activity of water soluble Cu(I), Ag(I) and Au(I) complexes supported by hydrophilic alkyl phosphine ligands | Journal of inorganic biochemistry |
| 22091409 | 2011-01-01 | Copper and its complexes in medicine: a biochemical approach | Molecular biology international |
