1,4-Dihydroxynaphthalene
Product Information
Molecular Formula
C10H8O2
Molecular Weight
160.17
Description
1,4-Dihydroxynaphthalene (CAS# 571-60-8) is a useful research chemical.
Synonyms
naphthalene-1,4-diol
IUPAC Name
naphthalene-1,4-diol
SMILES
C1=CC=C2C(=C1)C(=CC=C2O)O
InChI
InChI=1S/C10H8O2/c11-9-5-6-10(12)8-4-2-1-3-7(8)9/h1-6,11-12H
InChI Key
PCILLCXFKWDRMK-UHFFFAOYSA-N
Boiling Point
391 °C at 760 mmHg
Melting Point
188-192 °C
Purity
Techincal grade
Density
1.33 g/cm3
Appearance
Brown to greyish powder
Storage
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Refractive Index
1.5178 (estimate)
LogP
2.25100
Safety Information
Hazards
H302:
Harmful if swallowed.
H315:
Causes skin irritation.
H318:
Causes serious eye damage.
Harmful if swallowed.
H315:
Causes skin irritation.
H318:
Causes serious eye damage.
Precautionary Statement
P261, P264, P270, P271, P273, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P310, P312, P321, P330, P332+P313, P362, P403+P233, P405, and P501
Signal Word
Danger
Computed Properties
XLogP3
1.8
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
2
Rotatable Bond Count
0
Exact Mass
160.052429494 g/mol
Monoisotopic Mass
160.052429494 g/mol
Topological Polar Surface Area
40.5Ų
Heavy Atom Count
12
Formal Charge
0
Complexity
140
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-114133497-A | Water-based polymer emulsion and preparation method and application thereof | 2021-11-26 |
| CN-113845775-A | Preparation method of hyperbranched polymer modified boron nitride heat-conducting and insulating composite material | 2021-11-08 |
| CN-113637153-A | Multi-block polyether type high-molecular surfactant and preparation method and application thereof | 2021-10-18 |
| CN-113637154-A | Nonionic polyether type high-molecular surfactant and preparation method and application thereof | 2021-10-18 |
| CN-113637155-A | Anionic polyether type high-molecular surfactant and preparation method thereof | 2021-10-18 |
| CN-113880977-A | Olefin polymerization catalyst, preparation method and application | 2021-10-18 |
| CN-113773484-A | Preparation method of mining polyether polyol with high compressive strength | 2021-09-10 |
| CN-113461932-A | Preparation method of polyaryletherketone | 2021-07-29 |
| CN-113527660-A | Preparation of artificial fungus black material and antioxidation application | 2021-07-09 |
| CN-113683771-A | Preparation of artificial fungus black material and application of ultraviolet protection | 2021-07-09 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 22682920 | 2012-07-15 | A laccase-catalysed one-pot synthesis of aminonaphthoquinones and their anticancer activity | Bioorganic & medicinal chemistry |
| 22530964 | 2012-05-18 | Three different dimerizations of 2-bromo-3-methyl-1,4-naphthoquinones | The Journal of organic chemistry |
| 22220566 | 2012-03-08 | Discovery and synthesis of hydronaphthoquinones as novel proteasome inhibitors | Journal of medicinal chemistry |
| 20055453 | 2010-02-11 | Rational design of indoleamine 2,3-dioxygenase inhibitors | Journal of medicinal chemistry |
| 20127150 | 2010-02-01 | Naphthoquinones and anthraquinones from scent glands of a dyspnoid Harvestman, Paranemastoma quadripunctatum | Journal of chemical ecology |
| 19938843 | 2009-12-18 | N-Heterocyclic carbene-catalyzed monoacylation of 1,4-naphthoquinones with aldehydes | The Journal of organic chemistry |
| 19893237 | 2009-11-01 | 5-Amino-1-naphthol: two-dimensional sheets built up from R(4)(4)(18) rings formed by O-H...N, N-H...O and pi-pi interactions | Acta crystallographica. Section C, Crystal structure communications |
| 19753562 | 2009-10-01 | Synthesis and cytotoxic evaluation of 6-(3-pyrazolylpropyl) derivatives of 1,4-naphthohydroquinone-1,4-diacetate | Archiv der Pharmazie |
| 19338340 | 2009-04-01 | Pivotal role for two electron reduction in 2,3-dimethoxy-1,4-naphthoquinone and 2-methyl-1,4-naphthoquinone metabolism and kinetics in vivo that prevents liver redox stress | Chemical research in toxicology |
| 18708272 | 2009-03-01 | 2,3-Disubstituted-1,4-naphthoquinones, 12H-benzo[b]phenothiazine-6,11-diones and related compounds: synthesis and biological evaluation as potential antiproliferative and antifungal agents | European journal of medicinal chemistry |
