1,8-bis-(Hydroxymethyl)anthracene
Product Information
Molecular Formula
C16H14O2
Molecular Weight
238.28
Description
1,8-bis-(Hydroxymethyl)anthracene is an important prodrug whose main function is particularly significant in the biosynthesis of different anti-tumor drugs that are effective against leukemias and lymphomas and other hematological malignancies, especially the development of anthracyclines.
Synonyms
1,8-BIS(HYDROXYMETHYL)ANTHRACENE; 1,8-BIS(HYDROXYMETHYL)ANTHRACENE 98+%
IUPAC Name
[8-(hydroxymethyl)anthracen-1-yl]methanol
SMILES
C1=CC2=CC3=C(C=C2C(=C1)CO)C(=CC=C3)CO
InChI
InChI=1S/C16H14O2/c17-9-13-5-1-3-11-7-12-4-2-6-14(10-18)16(12)8-15(11)13/h1-8,17-18H,9-10H2
InChI Key
GSHJWFSWKUADLL-UHFFFAOYSA-N
Boiling Point
504.608°C at 760 mmHg
Melting Point
217°C
Purity
>98.0%(GC)
Density
1.286g/cm3
Appearance
Light yellow to Yellow to Green powder to crystal
Safety Information
Hazards
H315:
Causes skin irritation.
H319:
Causes serious eye irritation.
Causes skin irritation.
H319:
Causes serious eye irritation.
Precautionary Statement
P264:
Wash thoroughly after handling.
P280:
Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:
IF ON SKIN:
Wash with plenty of soap and water.
P332+P313:
If skin irritation occurs:
Get medical advice/attention.
P337+P313:
If eye irritation persists:
Get medical advice/attention.
P362+P364:
Take off contaminated clothing. [As modified by IV ATP].
And wash it before reuse. [Added by IV ATP].
Wash thoroughly after handling.
P280:
Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:
IF ON SKIN:
Wash with plenty of soap and water.
P332+P313:
If skin irritation occurs:
Get medical advice/attention.
P337+P313:
If eye irritation persists:
Get medical advice/attention.
P362+P364:
Take off contaminated clothing. [As modified by IV ATP].
And wash it before reuse. [Added by IV ATP].
Computed Properties
XLogP3
2.7
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
2
Rotatable Bond Count
2
Exact Mass
238.099379685 g/mol
Monoisotopic Mass
238.099379685 g/mol
Topological Polar Surface Area
40.5Ų
Heavy Atom Count
18
Formal Charge
0
Complexity
252
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-114031736-A | Modified phenolic resin for photoresist, preparation method thereof and photoresist composition | 2021-12-17 |
| JP-2021134343-A | A reactive mixture containing a plurality of reactive components and a polymer having an aryl ether ketone structure obtained from this mixture. | 2020-02-27 |
| CN-109020878-A | A kind of fluorescent molecule, preparation method and application identifying mercury ion | 2018-10-30 |
| KR-102074200-B1 | Low temperature curable organic dielectrics composition and method for preparing organic insulating film using the same | 2018-05-02 |
| KR-20190126616-A | Low temperature curable organic dielectrics composition and method for preparing organic insulating film using the same | 2018-05-02 |
| JP-2019116471-A | Dental resin composition and resin block for dental cutting comprising the same | 2017-12-26 |
| JP-2019108231-A | Gas generating material, method of manufacturing gas generating material, and micro pump | 2017-12-15 |
| JP-2018060205-A | Photosensitive resin composition, method for producing cured relief pattern, semiconductor device and display device | 2017-11-06 |
| JP-6454769-B2 | Photosensitive resin composition, method for producing cured relief pattern, semiconductor device and display device | 2017-11-06 |
| JP-2018162434-A | Phenolic hydroxyl group-containing resin, photosensitive resin composition, semiconductor device and electronic device | 2017-03-24 |
