2-(2-(Diphenylphosphino)ethyl)pyridine

Product Information

Molecular Formula:
C19H18NP
Molecular Weight:
291.33
Description
2-(2-(Diphenylphosphino)ethyl)pyridine is a chiral phosphine ligand for enantioselective synthesis with high yield and high enantioselective results.
Synonyms
1-(Diphenylphosphino)-2-(2-pyridyl)ethane, Diphenyl(2-(pyridin-2-yl)ethyl)phosphine
IUPAC Name
diphenyl(2-pyridin-2-ylethyl)phosphane
Canonical SMILES
C(Cc1ccccn1)P(c2ccccc2)c3ccccc3
InChI
InChI=1S/C19H18NP/c1-3-10-18(11-4-1)21(19-12-5-2-6-13-19)16-14-17-9-7-8-15-20-17/h1-13,15H,14,16H2
InChI Key
ARSGXAZDYSTSKI-UHFFFAOYSA-N
Melting Point
58-62°C
Flash Point
Not applicable
Purity
95%

Safety Information

Hazards
H315 - H319 - H335
Precautionary Statement
P261 - P305 + P351 + P338
Signal Word
Warning

Computed Properties

XLogP3
3.6
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
1
Rotatable Bond Count
5
Exact Mass
291.117686576 g/mol
Monoisotopic Mass
291.117686576 g/mol
Topological Polar Surface Area
12.9Ų
Heavy Atom Count
21
Formal Charge
0
Complexity
263
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes

Patents

Publication Number Title Priority Date
US-2020405874-A1 Methods of preparing cell-binding agent-drug conjugates 2019-03-21
WO-2020191306-A1 Methods of preparing cell-binding agent-drug conjugates 2019-03-21
TW-202102270-A Methods of preparing cell-binding agent-drug conjugates 2019-03-21
AU-2020240310-A1 Methods of preparing cell-binding agent-drug conjugates 2019-03-21
CA-3133802-A1 Methods of preparing cell-binding agent-drug conjugates 2019-03-21
CN-113631194-A Method for preparing cell-binding agent-drug conjugates 2019-03-21
EP-3941527-A1 Methods of preparing cell-binding agent-drug conjugates 2019-03-21
IL-286560-D0 Methods for making drug couplings - cell binding material 2019-03-21
KR-20220022112-A Methods of Preparing Cell-Binding Agent-Drug Conjugates 2019-03-21
WO-2020152200-A1 Process for preparation of heteroarylketones 2019-01-25
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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