2-(2-(Diphenylphosphino)ethyl)pyridine
Product Information
Molecular Formula
C19H18NP
Molecular Weight
291.33
Description
2-(2-(Diphenylphosphino)ethyl)pyridine is a chiral phosphine ligand for enantioselective synthesis with high yield and high enantioselective results.
Synonyms
1-(Diphenylphosphino)-2-(2-pyridyl)ethane, Diphenyl(2-(pyridin-2-yl)ethyl)phosphine
IUPAC Name
diphenyl(2-pyridin-2-ylethyl)phosphane
SMILES
C(Cc1ccccn1)P(c2ccccc2)c3ccccc3
InChI
InChI=1S/C19H18NP/c1-3-10-18(11-4-1)21(19-12-5-2-6-13-19)16-14-17-9-7-8-15-20-17/h1-13,15H,14,16H2
InChI Key
ARSGXAZDYSTSKI-UHFFFAOYSA-N
Melting Point
58-62°C
Flash Point
Not applicable
Purity
95%
Safety Information
Hazards
H315 - H319 - H335
Precautionary Statement
P261 - P305 + P351 + P338
Signal Word
Warning
Computed Properties
XLogP3
3.6
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
1
Rotatable Bond Count
5
Exact Mass
291.117686576 g/mol
Monoisotopic Mass
291.117686576 g/mol
Topological Polar Surface Area
12.9Ų
Heavy Atom Count
21
Formal Charge
0
Complexity
263
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| US-2020405874-A1 | Methods of preparing cell-binding agent-drug conjugates | 2019-03-21 |
| WO-2020191306-A1 | Methods of preparing cell-binding agent-drug conjugates | 2019-03-21 |
| TW-202102270-A | Methods of preparing cell-binding agent-drug conjugates | 2019-03-21 |
| AU-2020240310-A1 | Methods of preparing cell-binding agent-drug conjugates | 2019-03-21 |
| CA-3133802-A1 | Methods of preparing cell-binding agent-drug conjugates | 2019-03-21 |
| CN-113631194-A | Method for preparing cell-binding agent-drug conjugates | 2019-03-21 |
| EP-3941527-A1 | Methods of preparing cell-binding agent-drug conjugates | 2019-03-21 |
| IL-286560-D0 | Methods for making drug couplings - cell binding material | 2019-03-21 |
| KR-20220022112-A | Methods of Preparing Cell-Binding Agent-Drug Conjugates | 2019-03-21 |
| WO-2020152200-A1 | Process for preparation of heteroarylketones | 2019-01-25 |
