2-(3,4-Epoxycyclohexyl)ethyltrimethoxysilane
Product Information
Molecular Formula
C11H22O4Si
Molecular Weight
246.38
Description
2-(3,4-Epoxycyclohexyl)ethyltrimethoxysilane is a silane coupling agent used in biomedical research for the manufacture of drug delivery systems. It aids in creating stable, covalent bonds between organic and inorganic substances to optimize pharmaceutical properties.
Synonyms
2-(7-Oxabicyclo[4.1.0]hept-3-yl)ethyl-trimethoxysilane,3-(2-Trimethoxysilylethyl)cyclohexene oxide,[2-(3,4-Epoxycyclohexyl)ethyl]trimethoxysilane
IUPAC Name
trimethoxy-[2-(7-oxabicyclo[4.1.0]heptan-3-yl)ethyl]silane
SMILES
CO[Si](CCC1CCC2OC2C1)(OC)OC
InChI
InChI=1S/C11H22O4Si/c1-12-16(13-2,14-3)7-6-9-4-5-10-11(8-9)15-10/h9-11H,4-8H2,1-3H3
InChI Key
DQZNLOXENNXVAD-UHFFFAOYSA-N
Boiling Point
310 °C
Flash Point
136 °C(276.8 °F)
Purity
98%
Density
1.065 g/mL at 25 °C (lit.)
Appearance
Colorless to Almost colorless clear liquid
Refractive Index
1.451 (lit.)
Safety Information
Hazards
H319:
Causes serious eye irritation.
H351:
Suspected of causing cancer.
Causes serious eye irritation.
H351:
Suspected of causing cancer.
Precautionary Statement
P201:
Obtain special instructions before use.
P202:
Do not handle until all safety precautions have been read and understood.
P280:
Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313:
If exposed or concerned:
Get medical advice/attention.
P337+P313:
If eye irritation persists:
Get medical advice/attention.
P501:
Dispose of contents/container in accordance with local/regional/national/international regulations.
Obtain special instructions before use.
P202:
Do not handle until all safety precautions have been read and understood.
P280:
Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313:
If exposed or concerned:
Get medical advice/attention.
P337+P313:
If eye irritation persists:
Get medical advice/attention.
P501:
Dispose of contents/container in accordance with local/regional/national/international regulations.
Signal Word
Warning
Computed Properties
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
4
Rotatable Bond Count
6
Exact Mass
246.12873571 g/mol
Monoisotopic Mass
246.12873571 g/mol
Topological Polar Surface Area
40.2Ų
Heavy Atom Count
16
Formal Charge
0
Complexity
224
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
3
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| JP-2022040324-A | Adhesive composition and adhesive film | 2022-01-19 |
| JP-2022040236-A | Packaging materials and products | 2022-01-07 |
| JP-2022033262-A | Adhesive film | 2022-01-04 |
| CN-114163965-A | Bi-component solvent-free polyurethane adhesive for solar backboard | 2021-12-24 |
| CN-114133911-A | Solvent-free bi-component polyurethane adhesive and application thereof | 2021-12-23 |
| JP-2022036138-A | Adhesive layer and adhesive film | 2021-12-23 |
| JP-2022036139-A | Optical film with adhesive layer | 2021-12-23 |
| JP-2022043212-A | Optical film with adhesive layer | 2021-12-23 |
| CN-114133851-A | Organosilicon modified hydroxyl polyacrylate dispersion and preparation method and application thereof | 2021-12-20 |
| CN-114031757-A | Nano silicon dioxide modified polyester and preparation method and application thereof | 2021-12-16 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 22103157 | 2011-08-01 | Preparation and characterization of the transparent hybrids of silicone epoxy resin and titanium dioxide nanoparticles via sol-gel reactions | Journal of nanoscience and nanotechnology |
| 20352849 | 2010-01-01 | Synthesis of functionalized mesoporous material with various organo-silanes | Journal of nanoscience and nanotechnology |
| 22163541 | 2010-01-01 | Nitrite biosensing via selective enzymes--a long but promising route | Sensors (Basel, Switzerland) |
| 19580298 | 2009-07-30 | Refractive index control and Rayleigh scattering properties of transparent TiO2 nanohybrid polymer | The journal of physical chemistry. B |
| 19376341 | 2009-06-30 | Amperometric biosensor for hydrogen peroxide based on coimmobilized horseradish peroxidase and methylene green in ormosils matrix with multiwalled carbon nanotubes | Talanta |
| 18823130 | 2008-11-04 | Size-controlled, one-pot synthesis, characterization, and biological applications of epoxy-organosilica particles possessing positive zeta potential | Langmuir : the ACS journal of surfaces and colloids |
| 17207600 | 2007-03-12 | Application of lactate amperometric sol-gel biosensor to sequential injection determination of L-lactate | Journal of pharmaceutical and biomedical analysis |
| 16125221 | 2006-03-01 | A conductive ormosil encapsulated with ferrocene conjugate and multiwall carbon nanotubes for biosensing application | Biomaterials |
| 16099155 | 2006-02-15 | Amperometric biosensor for hydrogen peroxide based on ferrocene-bovine serum albumin and multiwall carbon nanotube modified ormosil composite | Biosensors & bioelectronics |
| 15790108 | 2005-03-01 | Chiral speciation and determination of DL-selenomethionine enantiomers on a novel chiral ligand-exchange stationary phase | Analytical sciences : the international journal of the Japan Society for Analytical Chemistry |
