2,3-Epoxypropyl 4'-methoxyphenyl ether
Product Information
Molecular Formula
C10H12O3
Molecular Weight
180.20
Description
An impurity of Ranolazine. Ranolazine is an oral antianginal agent that inhibits the late sodium current (INa) in cardiac myocytes, reducing intracellular calcium overload and improving myocardial relaxation without affecting heart rate or blood pressure. It is indicated as adjunctive therapy for chronic angina in patients inadequately controlled with other agents.
Synonyms
2-((4-Methoxyphenoxy)methyl)oxirane; Ranolazine Para epoxide; 1-(4-Methoxyphenoxy)-2,3-epoxypropane; 1-(p-Methoxyphenoxy)-2,3-epoxypropane; 1,2-Epoxy-3-(p-methoxyphenoxy)propane; Glycidyl 4-methoxyphenyl ether; 2,3-Epoxypropyl-4-methoxyphenyl ether; p-Methoxyphenyl glycidyl ether; Methoxyphenyl glycidyl ether; Glycidyl p-methoxyphenyl ether; 2-(p-Methoxyphenoxymethyl)oxirane; 2,3-Epoxypropyl p-methoxyphenyl ether
IUPAC Name
2-[(4-methoxyphenoxy)methyl]oxirane
SMILES
COC1=CC=C(C=C1)OCC2CO2
InChI
InChI=1S/C10H12O3/c1-11-8-2-4-9(5-3-8)12-6-10-7-13-10/h2-5,10H,6-7H2,1H3
InChI Key
AVWGFHZLPMLKBL-UHFFFAOYSA-N
Boiling Point
287.9°C at 760mmHg
Melting Point
45-48°C
Flash Point
Not applicable
Purity
95%
Density
1.142g/cm3
Appearance
White solid
Storage
Store at RT
Computed Properties
XLogP3
1.6
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
3
Rotatable Bond Count
4
Exact Mass
180.078644241 g/mol
Monoisotopic Mass
180.078644241 g/mol
Topological Polar Surface Area
31Ų
Heavy Atom Count
13
Formal Charge
0
Complexity
152
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
1
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-113387873-A | Substituted diaryl compound, preparation method and application thereof | 2021-06-15 |
| WO-2022056053-A1 | Polypropylene polymer having ultra-high melt flow rate | 2020-09-09 |
| WO-2022049070-A1 | Electrically conductive epoxy resin coating and electrostatically dissipative floor | 2020-09-01 |
| WO-2022049071-A1 | Transparent electrically conductive epoxy resin coating and electrostatic dissipative floor | 2020-09-01 |
| WO-2022046560-A1 | Fluorescent dye loaded polymeric taggants for depth determination in drilling wells | 2020-08-24 |
| WO-2022030276-A1 | Photocationic curable composition and curable dental composition | 2020-08-07 |
| CN-111621031-A | Preparation method and application of mimic enzyme MOF-based chiral separation material | 2020-06-28 |
| JP-2021116356-A | Photocationic curable composition | 2020-01-27 |
| JP-2021109956-A | Cationic curable composition | 2020-01-09 |
| WO-2021083744-A1 | Impregnation resin for a woven or stitched fabric | 2019-10-28 |
