2,4-Dimethoxyphenylboronic Acid
Product Information
Molecular Formula
C8H11O4B
Molecular Weight
181.98
Description
2,4-Dimethoxyphenylboronic acid can be used: As a reactant in meatal-catalyzed Suzuki−Miyaura cross-coupling reaction; To prepare hydroxy(trimethoxy)phenanthrene by cross-coupling with bromo(benzyloxy)methoxybenzaldehyde followed by condensation and debenzylation reaction; To synthesize 2,4-dimethoxy-1-(trifluoromethyl)benzene via Cu-catalyzed trifluoromethylation reaction.
Synonyms
(2,4-dimethoxyphenyl)boronic acid; (2,4-dimethoxyphenyl)boronic acid
IUPAC Name
(2,4-dimethoxyphenyl)boronic acid
SMILES
B(C1=C(C=C(C=C1)OC)OC)(O)O
InChI
InChI=1S/C8H11BO4/c1-12-6-3-4-7(9(10)11)8(5-6)13-2/h3-5,10-11H,1-2H3
InChI Key
SQTUYFKNCCBFRR-UHFFFAOYSA-N
Boiling Point
361.1 °C at 760 mmHg
Melting Point
125-127 °C (lit.)
Flash Point
Not applicable
Purity
95 %
Density
1.19 g/cm3
LogP
-0.61640
Safety Information
Precautionary Statement
P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501
Signal Word
Warning
Computed Properties
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
4
Rotatable Bond Count
3
Exact Mass
182.0750390 g/mol
Monoisotopic Mass
182.0750390 g/mol
Topological Polar Surface Area
58.9Ų
Heavy Atom Count
13
Formal Charge
0
Complexity
153
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-114016060-A | Synthetic method of phenolic compound | 2021-11-23 |
| CN-113683498-A | Green light material based on 9-fluorenone structural framework and preparation method and application thereof | 2021-09-07 |
| CN-113930790-A | Synthetic method of aryl selenide compound | 2021-09-07 |
| CN-113387838-A | 2, 3-bis (2, 4-dimethoxyphenyl) maleonitrile, dimer compound, preparation method and application thereof | 2021-06-08 |
| CN-111808434-A | Method for preparing naphthol AS series azo dye | 2020-07-20 |
| CN-111808434-B | Method for preparing naphthol AS series azo dye | 2020-07-20 |
| CN-111559990-A | Micromolecular oxathiazine derivative and application thereof | 2020-05-29 |
| CN-111559990-B | Micromolecular oxathiazine derivative and application thereof | 2020-05-29 |
| WO-2021238587-A1 | Micromolecular oxathiazine derivative and use thereof | 2020-05-29 |
| CN-111440137-A | 3, 4-benzocoumarin derivative and preparation method and application thereof | 2020-04-28 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 21582929 | 2009-06-24 | 2,4-Dibutoxy-phenyl-boronic acid | Acta crystallographica. Section E, Structure reports online |
| 4946 | 1976-01-01 | Policy statement on the changeover to Système International (SI) in Acta anaesthesiological Scandinavica | Acta anaesthesiologica Scandinavica |
