2,6-Dihydroxynaphthalene
Product Information
Molecular Formula
C10H8O2
Molecular Weight
160.17
Description
2,6-Dihydroxynaphthalene can produce convulsions in mice. Monooxylosylated 2,6-Dihydroxynaphthalene exhibits antiproliferative activity towards certain cells.
Synonyms
naphthalene-2,6-diol
IUPAC Name
naphthalene-2,6-diol
SMILES
C1=CC2=C(C=CC(=C2)O)C=C1O
InChI
InChI=1S/C10H8O2/c11-9-3-1-7-5-10(12)4-2-8(7)6-9/h1-6,11-12H
InChI Key
MNZMMCVIXORAQL-UHFFFAOYSA-N
Boiling Point
246.06 °C (rough estimate)
Melting Point
223-225 °C
Purity
98 %
Density
1.33 g/cm3
Appearance
Plates or crystals
Storage
Keep container tightly sealed. Store in cool, dry conditions in well sealed containers.
Refractive Index
1.5418 (estimate)
LogP
2.25100
Vapor Pressure
0.00000715 [mmHg]
Safety Information
Hazards
H315:
Causes skin irritation.
H319:
Causes serious eye irritation.
Causes skin irritation.
H319:
Causes serious eye irritation.
Precautionary Statement
P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501
Signal Word
Warning
Computed Properties
XLogP3
2.3
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
2
Rotatable Bond Count
0
Exact Mass
160.052429494 g/mol
Monoisotopic Mass
160.052429494 g/mol
Topological Polar Surface Area
40.5Ų
Heavy Atom Count
12
Formal Charge
0
Complexity
140
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| JP-2022040214-A | Resin composition | 2022-01-05 |
| CN-114134590-A | High-performance liquid crystal polyarylester fiber and preparation method and production equipment thereof | 2021-12-30 |
| JP-2022028036-A | Dry films, cured products, and electronic components | 2021-12-21 |
| JP-2022031285-A | Resin composition, sheet-like laminated material, printed wiring board and semiconductor device | 2021-11-24 |
| JP-2022022261-A | Resin composition | 2021-11-22 |
| JP-2022027768-A | Resin composition | 2021-11-16 |
| CN-113845775-A | Preparation method of hyperbranched polymer modified boron nitride heat-conducting and insulating composite material | 2021-11-08 |
| CN-113929846-A | High-carbon-formation-rate water-soluble phenolic resin and preparation method thereof | 2021-10-22 |
| JP-2022017350-A | Adhesive sheet with support | 2021-10-19 |
| CN-113637153-A | Multi-block polyether type high-molecular surfactant and preparation method and application thereof | 2021-10-18 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 20140918 | 2010-03-15 | A light-controlled molecular brake with complete ON-OFF rotation | Chemistry (Weinheim an der Bergstrasse, Germany) |
| 20099891 | 2010-02-19 | Synthesis, properties, crystal structures, and semiconductor characteristics of naphtho[1,2-b:5,6-b']dithiophene and -diselenophene derivatives | The Journal of organic chemistry |
| 20689716 | 2010-01-01 | New thermal and microbial resistant metal-containing epoxy polymers | Bioinorganic chemistry and applications |
| 19615911 | 2009-08-15 | Chromane derivatives of small aromatic molecules: Chemoenzymatic synthesis and growth inhibitory activity on human tumor cell line LoVo WT | Bioorganic & medicinal chemistry |
| 19055354 | 2009-01-16 | Experimental and theoretical studies on constitutional isomers of 2,6-dihydroxynaphthalene carbaldehydes. Effects of resonance-assisted hydrogen bonding on the electronic absorption spectra | The Journal of organic chemistry |
| 21202680 | 2008-05-30 | 4,4'-(2,6-Dihydroxy-naphthalene-1,5-diyldimethyl-ene)dipyridinium bis-(per-chlorate) | Acta crystallographica. Section E, Structure reports online |
| 17479998 | 2007-06-04 | Toward high-generation rotaxane dendrimers that incorporate a ring component on every branch: noncovalent synthesis of a dendritic [10]pseudorotaxane with 13 molecular components | Chemistry, an Asian journal |
| 16539380 | 2006-03-23 | Selective antiproliferative activity of hydroxynaphthyl-beta-D-xylosides | Journal of medicinal chemistry |
| 15809167 | 2005-05-02 | The influence of aromatic residues in hydraphile spacer units: assay by ion selective electrode methods and in bacteria | Bioorganic & medicinal chemistry |
| 15807536 | 2005-04-12 | Hydroxynaphthaldehyde phosphate derivatives as potent covalent Schiff base inhibitors of fructose-1,6-bisphosphate aldolase | Biochemistry |
