2,7-Dihydroxynaphthalene
Product Information
Molecular Formula
C10H8O2
Molecular Weight
160.17
Description
Applications: 2,7-Naphthalenediol is a reagent used in the preparation of monomers of high carbon materials. Also used in the synthesis of splitomicin analogues.
Synonyms
naphthalene-2,7-diol
IUPAC Name
naphthalene-2,7-diol
SMILES
C1=CC(=CC2=C1C=CC(=C2)O)O
InChI
InChI=1S/C10H8O2/c11-9-3-1-7-2-4-10(12)6-8(7)5-9/h1-6,11-12H
InChI Key
DFQICHCWIIJABH-UHFFFAOYSA-N
Boiling Point
246.06 °C (rough estimate)
Melting Point
184-189 °C
Density
1.33 g/cm3
Appearance
Light yellow to grey needle crystal
Application
Used in oxidative hair dye formulations.
Storage
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Refractive Index
1.5418 (estimate)
LogP
2.25100
Safety Information
Hazards
H315:
Causes skin irritation.
H319:
Causes serious eye irritation.
Causes skin irritation.
H319:
Causes serious eye irritation.
Precautionary Statement
P261, P264, P270, P271, P272, P273, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P310, P312, P321, P330, P332+P313, P333+P313, P337+P313, P362, P363, P391, P403+P233, P405, and P501
Signal Word
Danger
Computed Properties
XLogP3
2.3
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
2
Rotatable Bond Count
0
Exact Mass
160.052429494 g/mol
Monoisotopic Mass
160.052429494 g/mol
Topological Polar Surface Area
40.5Ų
Heavy Atom Count
12
Formal Charge
0
Complexity
142
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-114177098-A | Artificial melanin-like hair dye with oxidation resistance, and preparation method and use method thereof | 2021-12-16 |
| CN-114137046-A | Method for detecting content of sodium carboxymethylcellulose in medical and cosmetic filler | 2021-11-29 |
| CN-114011242-A | Carboxylated poly (arylene ether nitrile) ultrafiltration membrane and preparation method thereof | 2021-11-22 |
| CN-113845775-A | Preparation method of hyperbranched polymer modified boron nitride heat-conducting and insulating composite material | 2021-11-08 |
| CN-114010511-A | Hair dye, color developing agent and using method of double-agent oxidation type hair dye | 2021-11-08 |
| CN-113929846-A | High-carbon-formation-rate water-soluble phenolic resin and preparation method thereof | 2021-10-22 |
| CN-113637153-A | Multi-block polyether type high-molecular surfactant and preparation method and application thereof | 2021-10-18 |
| CN-113637154-A | Nonionic polyether type high-molecular surfactant and preparation method and application thereof | 2021-10-18 |
| CN-113637155-A | Anionic polyether type high-molecular surfactant and preparation method thereof | 2021-10-18 |
| CN-113880700-A | Fluorescent naphthalene ring [3] arene nonporous self-adaptive crystal and preparation method and application thereof | 2021-10-13 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 28940058 | 2018-01-01 | Functional cardiotoxicity assessment of cosmetic compounds using human-induced pluripotent stem cell-derived cardiomyocytes | Archives of toxicology |
| 23016299 | 2012-06-01 | [Simultaneous determination of seven naphthalenediols in cosmetics by reversed-phase high performance liquid chromatography] | Se pu = Chinese journal of chromatography |
| 22689422 | 2012-01-01 | Condensation of 2-naphthol and naphthalenediols with o-dichlorobenzene in the presence of aluminum halides | Chemical & pharmaceutical bulletin |
| 22065129 | 2011-09-01 | 1,5-Dichloro-3(2,7),7(2,7)-dinaphthal-ena-2,4,6,8-tetra-oxa-1(2,6),5(2,6)-di(1,3,5-triazina)octa-phane | Acta crystallographica. Section E, Structure reports online |
| 20957269 | 2010-12-14 | Monoclinic CuO nanoflowers on resin support: recyclable catalyst to obtain perylene compound | Chemical communications (Cambridge, England) |
| 21138250 | 2010-12-01 | Influence of the polymer backbone structure on the properties of aromatic ionomers with pendant sulfobenzoyl side chains for use as proton-exchange membranes | ACS applied materials & interfaces |
| 21587843 | 2010-06-09 | 2,7-Bis(prop-2-yn-1-yl-oxy)naphthalene | Acta crystallographica. Section E, Structure reports online |
| 20351110 | 2010-05-28 | A new group of aromatic prenyltransferases in fungi, catalyzing a 2,7-dihydroxynaphthalene 3-dimethylallyl-transferase reaction | The Journal of biological chemistry |
| 20030355 | 2010-05-04 | Photoinduced formation of shape-selective Pt nanoparticles | Langmuir : the ACS journal of surfaces and colloids |
| 18682327 | 2008-09-01 | Chemoenzymatic syntheses of prenylated aromatic small molecules using Streptomyces prenyltransferases with relaxed substrate specificities | Bioorganic & medicinal chemistry |
