2-(Bromomethyl)phenylboronic Acid
Product Information
Molecular Formula
C7H8BrO2B
Molecular Weight
214.85
Description
2-(Bromomethyl)phenylboronic acid can be used as a reactant to synthesize: Boronic acid-functionalized benzyl viologen (o-BBV) from 4,4'-bipyridine. o-BBV finds its application as a chemosensor to sense glucose in aqueous water; 2-(azidomethyl)phenylboronic acid, which is further employed in the preparation of isoquinoline derivatives.; Aryl boronic acid derivatives as fluorescent probe for hydrogen peroxide detection. Reactant involved in: Studies of carbon-boron bond cleavage of phenylboronate-pendant cyclen; Development of a sensory system to detect glucose or other monosaccharides and hydroxycarboxylates; Synthesis of boronated triaryl and tetraaryl phosphonium salts used in cytotoxicity studies; Colorimetry and fluorometry mercury determination with chemosensors composed of rhodamine and boronic acid groups; Synthesis of imidazolium-containing boronic acids used as fluoride ion sensors; Reactions with adenine for molecules with antiinflammatory antitumor activities.
Synonyms
[2-(bromomethyl)phenyl]boronic acid; [2-(bromomethyl)phenyl]boronic acid
IUPAC Name
[2-(bromomethyl)phenyl]boronic acid
SMILES
B(C1=CC=CC=C1CBr)(O)O
InChI
InChI=1S/C7H8BBrO2/c9-5-6-3-1-2-4-7(6)8(10)11/h1-4,10-11H,5H2
InChI Key
MYVJCOQGXCONPE-UHFFFAOYSA-N
Boiling Point
358.5 °C at 760 mmHg
Melting Point
158-162 °C
Flash Point
Not applicable
Density
1.57 g/cm3
Storage
2-8 °C
LogP
0.26130
Safety Information
Hazards
H315 - H319 - H335
Precautionary Statement
P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501
Signal Word
Warning
Computed Properties
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
2
Rotatable Bond Count
2
Exact Mass
213.98007 g/mol
Monoisotopic Mass
213.98007 g/mol
Topological Polar Surface Area
40.5Ų
Heavy Atom Count
11
Formal Charge
0
Complexity
121
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-114045082-A | Composite coating with self-repairing, air-permeable and wear-resistant properties, and preparation method and application thereof | 2021-12-14 |
| CN-113278094-A | Cyclodextrin derivative and preparation method and application thereof | 2021-05-31 |
| CN-113278094-B | Cyclodextrin derivative and preparation method and application thereof | 2021-05-31 |
| CN-113754793-A | Phenylboronic acid grafted chitosan oligosaccharide derivative and preparation method and application thereof | 2020-06-05 |
| CN-111548714-A | Self-repairing water-based polymer composite coating agent and preparation method and application thereof | 2020-05-29 |
| CN-111423462-A | Tetraphenyl ethylene borate pyridine salt, preparation method and application thereof, and reagent and method for detecting fructose | 2020-04-27 |
| EP-3878891-A1 | Dynamic covalent hydrogels, precursors thereof and uses thereof | 2020-03-10 |
| WO-2021180795-A1 | Dynamic covalent hydrogels, precursors thereof and uses thereof | 2020-03-10 |
| KR-20210057700-A | Composition for cell imaging, and cell-material imaging method using the same | 2019-11-12 |
| WO-2021096263-A1 | Cell imaging composition and cellular material imaging method using same | 2019-11-12 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 21820888 | 2011-10-15 | Color changing block copolymer films for chemical sensing of simple sugars | Biosensors & bioelectronics |
