2-Di-tert-butylphosphino-3,4,5,6-tetramethyl-2',4',6'-triisopropyl-1,1'-biphenyl
Product Information
Molecular Formula
C33H53P
Molecular Weight
480.75
Description
Ligand used in a palladium-catalyzed amidation of aryl chlorides.
Synonyms
ditert-butyl-[2,3,4,5-tetramethyl-6-[2,4,6-tri(propan-2-yl)phenyl]phenyl]phosphine; ditert-butyl-[2,3,4,5-tetramethyl-6-[2,4,6-tri(propan-2-yl)phenyl]phenyl]phosphane
IUPAC Name
ditert-butyl-[2,3,4,5-tetramethyl-6-[2,4,6-tri(propan-2-yl)phenyl]phenyl]phosphane
SMILES
CC1=C(C(=C(C(=C1C)C2=C(C=C(C=C2C(C)C)C(C)C)C(C)C)P(C(C)(C)C)C(C)(C)C)C)C
InChI
InChI=1S/C33H53P/c1-19(2)26-17-27(20(3)4)30(28(18-26)21(5)6)29-24(9)22(7)23(8)25(10)31(29)34(32(11,12)13)33(14,15)16/h17-21H,1-16H3
InChI Key
RCRYEYMHBHPZQD-UHFFFAOYSA-N
Boiling Point
534.094 °C at 760 mmHg
Melting Point
168-172 °C
Flash Point
Not applicable
Purity
96 %
Appearance
Solid
LogP
10.66160
Safety Information
Precautionary Statement
P261, P264, P270, P271, P273, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, and P501
Signal Word
Warning
Computed Properties
XLogP3
9.9
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
0
Rotatable Bond Count
7
Exact Mass
480.38848869 g/mol
Monoisotopic Mass
480.38848869 g/mol
Topological Polar Surface Area
0Ų
Heavy Atom Count
34
Formal Charge
0
Complexity
600
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| WO-2022056051-A1 | Plasma kallikrein inhibitors | 2020-09-10 |
| WO-2021247781-A1 | Novel heteroaromatic compounds exhibiting antifungal activity and their method of use | 2020-06-05 |
| CN-111732573-A | Quinolone acid-aminopyrimidine compound and preparation method and application thereof | 2020-05-16 |
| WO-2021215544-A1 | Kras g12d protein inhibitors | 2020-04-24 |
| WO-2021215545-A1 | Anticancer combination therapy with n-(1-acryloyl-azetidin-3-yl)-2-((1h-indazol-3-yl)amino)methyl)-1h-imidazole-5-carboxamide inhibitor of kras-g12c | 2020-04-24 |
| WO-2021201120-A1 | Agent for treating inflammatory bowel disease, and amide compound or salt thereof | 2020-03-31 |
| WO-2021201126-A1 | Amide compound or salt thereof, pharmaceutical composition and histone deacetylase inhibitor | 2020-03-31 |
| WO-2021200824-A1 | Novel xanthenone derivative | 2020-03-30 |
| WO-2021188762-A1 | Boron-containing cyclic emissive compounds and color conversion film containing the same | 2020-03-20 |
| WO-2021185712-A1 | Heteroaromatic compounds for organic electroluminescent devices | 2020-03-17 |
