2-Dicyclohexylphosphino-2',6'-diisopropoxybiphenyl
Product Information
Molecular Formula
C30H43O2P
Molecular Weight
466.63
Description
Bulky phosphine ligand used in a palladium-catalyzed cross-coupling of aminoethyltrifluoroborates with electron-poor aryl bromides.
Synonyms
dicyclohexyl-[2-[2,6-di(propan-2-yloxy)phenyl]phenyl]phosphine; dicyclohexyl-[2-[2,6-di(propan-2-yloxy)phenyl]phenyl]phosphane
IUPAC Name
dicyclohexyl-[2-[2,6-di(propan-2-yloxy)phenyl]phenyl]phosphane
SMILES
CC(C)OC1=C(C(=CC=C1)OC(C)C)C2=CC=CC=C2P(C3CCCCC3)C4CCCCC4
InChI
InChI=1S/C30H43O2P/c1-22(2)31-27-19-13-20-28(32-23(3)4)30(27)26-18-11-12-21-29(26)33(24-14-7-5-8-15-24)25-16-9-6-10-17-25/h11-13,18-25H,5-10,14-17H2,1-4H3
InChI Key
MXFYYFVVIIWKFE-UHFFFAOYSA-N
Boiling Point
551.7 °C at 760 mmHg
Melting Point
123-126 °C
Purity
98 %
LogP
8.70060
Safety Information
Precautionary Statement
P261, P264, P270, P271, P273, P280, P301+P312, P302+P352, P304+P312, P304+P340, P305+P351+P338, P312, P321, P322, P330, P332+P313, P337+P313, P362, P363, and P501
Signal Word
Warning
Computed Properties
XLogP3
8.3
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
2
Rotatable Bond Count
8
Exact Mass
466.30006761 g/mol
Monoisotopic Mass
466.30006761 g/mol
Topological Polar Surface Area
18.5Ų
Heavy Atom Count
33
Formal Charge
0
Complexity
516
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-114085213-A | Preparation method of ARV-471 | 2022-01-20 |
| CN-114163465-A | Synthesis method of alkenyl borate compound | 2021-12-24 |
| CN-113999143-A | Fluorine aromatic amino acid and synthetic method thereof | 2021-12-06 |
| CN-113773245-A | Water-soluble double-targeting near-infrared fluorescent probe and preparation method thereof | 2021-10-11 |
| CN-113816889-A | 4-sulfimide-1H-pyrrole Mcl-1 inhibitor and anti-tumor medical application thereof | 2021-10-11 |
| CN-113816925-A | A trematopsin 3 "-tert-butyl-4 '- (2-hydroxyethoxy) -4" -pyrrolidin-1-yl [1, 1'; process for preparing 3 ', 1' ] -terphenyl-4-carboxylic acid | 2021-09-18 |
| CN-113636970-A | Isoindolone compound, preparation method and application thereof | 2021-09-13 |
| CN-113387876-A | Nickel-catalyzed direct reduction cross-coupling method for heterocyclic phosphonium salt and aryl bromide and product | 2021-07-21 |
| CN-113480416-A | Preparation method of aryl ketone | 2021-07-12 |
| CN-113354552-A | Synthetic method of V-type organic ligand, synthesized V-type organic ligand and application thereof | 2021-06-30 |
