2-Fluoro-4-methylphenylboronic Acid
Product Information
Molecular Formula
C7H8FO2B
Molecular Weight
153.95
Description
Reactant for: Water-accelerated Pd-Catalyzed Suzuki-Miyaura coupling.
Synonyms
(2-fluoro-4-methylphenyl)boronic acid; (2-fluoro-4-methylphenyl)boronic acid
IUPAC Name
(2-fluoro-4-methylphenyl)boronic acid
SMILES
B(C1=C(C=C(C=C1)C)F)(O)O
InChI
InChI=1S/C7H8BFO2/c1-5-2-3-6(8(10)11)7(9)4-5/h2-4,10-11H,1H3
InChI Key
LIXXGOMAGHXIMP-UHFFFAOYSA-N
Melting Point
228-233 °C (lit.)
Purity
≥ 95 %
Appearance
White to light brown powder or fibers
LogP
-0.18610
Safety Information
Precautionary Statement
P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, and P501
Signal Word
Warning
Computed Properties
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
3
Rotatable Bond Count
1
Exact Mass
154.0601378 g/mol
Monoisotopic Mass
154.0601378 g/mol
Topological Polar Surface Area
40.5Ų
Heavy Atom Count
11
Formal Charge
0
Complexity
132
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-114106056-A | Metal organic light-emitting material and application thereof in OLED device | 2021-12-02 |
| CN-113929635-A | 1, 6-diphenyl-1H-benzo [ d ] [1,2,3] triazole compound and preparation method and application thereof | 2021-11-09 |
| CN-113444038-A | 2-aryl isonicotinic acid amide LSD1/HDAC double-target inhibitor, and preparation method and application thereof | 2021-07-07 |
| CN-113444069-A | 2-aryl-4- (1H-pyrazol-3-yl) pyridine LSD1/HDAC double-target inhibitor | 2021-07-07 |
| CN-113527195-A | 5-aryl nicotinamide LSD1/HDAC double-target inhibitor, preparation method and application thereof | 2021-07-07 |
| CN-111592487-A | Hydroximic acid group-containing diarylethene LSD1/HDACs double-target inhibitor, and preparation method and application thereof | 2020-06-09 |
| CN-111559990-A | Micromolecular oxathiazine derivative and application thereof | 2020-05-29 |
| CN-111559990-B | Micromolecular oxathiazine derivative and application thereof | 2020-05-29 |
| WO-2021238587-A1 | Micromolecular oxathiazine derivative and use thereof | 2020-05-29 |
| CN-113666967-A | Organometallic compound, organic light emitting device including the same, and electronic apparatus including the organic light emitting device | 2020-05-14 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 20669927 | 2010-11-11 | Medicinal chemistry as a conduit for the modulation of quorum sensing | Journal of medicinal chemistry |
