2-Fluorophenylboronic Acid

Product Information

Molecular Formula:
C6H6FO2B
Molecular Weight:
139.92
Description
Reactant for: Preparation of phenylboronic catechol esters as promising anion receptors for polymer electrolytes; Diastereoselective synthesis of trisubstituted allylic alcohols via rhodium-catalyzed arylation; Site-selective Suzuki-Miyaura arylation reactions; Rh-catalyzed enantioselective addition reactions; Rhodium- and Palladium-catalyzed substitution reactions. Used for the preparation of biologically active biphenyls and arylboron difluoride Lewis acids.
Synonyms
(2-fluorophenyl)boronic acid; (2-fluorophenyl)boronic acid
IUPAC Name
(2-fluorophenyl)boronic acid
Canonical SMILES
B(C1=CC=CC=C1F)(O)O
InChI
InChI=1S/C6H6BFO2/c8-6-4-2-1-3-5(6)7(9)10/h1-4,9-10H
InChI Key
QCSLIRFWJPOENV-UHFFFAOYSA-N
Melting Point
101-110 °C (lit.)
Flash Point
Not applicable
Purity
≥ 95 %
LogP
-0.49450

Safety Information

Precautionary Statement
P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501
Signal Word
Warning

Computed Properties

Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
3
Rotatable Bond Count
1
Exact Mass
140.0444878 g/mol
Monoisotopic Mass
140.0444878 g/mol
Topological Polar Surface Area
40.5Ų
Heavy Atom Count
10
Formal Charge
0
Complexity
110
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes

Patents

Publication Number Title Priority Date
CN-114106058-A Preparation method and application of aggregation-induced emission platinum complex 2021-12-15
CN-114181144-A Fluorobiphenyl methyl resorcinol ether derivative, preparation method and application thereof 2021-12-06
CN-114163381-A Method for synthesizing (2, 6-diphenylpyridine-3, 5-diacyl) bis (benzophenone) and derivatives thereof 2021-12-01
CN-113968824-A 2,3, 5-trisubstituted pyrazine compound and preparation method and application thereof 2021-11-29
CN-113929635-A 1, 6-diphenyl-1H-benzo [ d ] [1,2,3] triazole compound and preparation method and application thereof 2021-11-09
CN-113788846-A Tricyclic thiazolo [5,4-d ] pyrimidone derivative and application thereof 2021-10-27
CN-113861166-A Preparation method of high-purity Voranolan fumarate 2021-10-18
CN-113897785-A Preparation method of layer-by-layer self-assembled semiconductor fiber and transistor sensor 2021-09-24
JP-2021152084-A Pest control method 2021-07-02
CN-113234010-A Compound, electron transport material, organic electroluminescent device and display device 2021-05-07

Literatures

PMID Publication Date Title Journal
18983140 2008-11-27 Discovery of boronic acids as novel and potent inhibitors of fatty acid amide hydrolase Journal of medicinal chemistry
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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