2-Fluorophenylboronic Acid
Product Information
Molecular Formula
C6H6FO2B
Molecular Weight
139.92
Description
Reactant for: Preparation of phenylboronic catechol esters as promising anion receptors for polymer electrolytes; Diastereoselective synthesis of trisubstituted allylic alcohols via rhodium-catalyzed arylation; Site-selective Suzuki-Miyaura arylation reactions; Rh-catalyzed enantioselective addition reactions; Rhodium- and Palladium-catalyzed substitution reactions. Used for the preparation of biologically active biphenyls and arylboron difluoride Lewis acids.
Synonyms
(2-fluorophenyl)boronic acid; (2-fluorophenyl)boronic acid
IUPAC Name
(2-fluorophenyl)boronic acid
SMILES
B(C1=CC=CC=C1F)(O)O
InChI
InChI=1S/C6H6BFO2/c8-6-4-2-1-3-5(6)7(9)10/h1-4,9-10H
InChI Key
QCSLIRFWJPOENV-UHFFFAOYSA-N
Melting Point
101-110 °C (lit.)
Flash Point
Not applicable
Purity
≥ 95 %
LogP
-0.49450
Safety Information
Precautionary Statement
P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501
Signal Word
Warning
Computed Properties
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
3
Rotatable Bond Count
1
Exact Mass
140.0444878 g/mol
Monoisotopic Mass
140.0444878 g/mol
Topological Polar Surface Area
40.5Ų
Heavy Atom Count
10
Formal Charge
0
Complexity
110
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-114106058-A | Preparation method and application of aggregation-induced emission platinum complex | 2021-12-15 |
| CN-114181144-A | Fluorobiphenyl methyl resorcinol ether derivative, preparation method and application thereof | 2021-12-06 |
| CN-114163381-A | Method for synthesizing (2, 6-diphenylpyridine-3, 5-diacyl) bis (benzophenone) and derivatives thereof | 2021-12-01 |
| CN-113968824-A | 2,3, 5-trisubstituted pyrazine compound and preparation method and application thereof | 2021-11-29 |
| CN-113929635-A | 1, 6-diphenyl-1H-benzo [ d ] [1,2,3] triazole compound and preparation method and application thereof | 2021-11-09 |
| CN-113788846-A | Tricyclic thiazolo [5,4-d ] pyrimidone derivative and application thereof | 2021-10-27 |
| CN-113861166-A | Preparation method of high-purity Voranolan fumarate | 2021-10-18 |
| CN-113897785-A | Preparation method of layer-by-layer self-assembled semiconductor fiber and transistor sensor | 2021-09-24 |
| JP-2021152084-A | Pest control method | 2021-07-02 |
| CN-113234010-A | Compound, electron transport material, organic electroluminescent device and display device | 2021-05-07 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 18983140 | 2008-11-27 | Discovery of boronic acids as novel and potent inhibitors of fatty acid amide hydrolase | Journal of medicinal chemistry |
