2-Iodo-5-methoxyphenylboronic Acid
Product Information
Molecular Formula
C7H8IO3B
Molecular Weight
277.85
Description
MIBA can be used to promote direct amidations of carboxylic acids and amines in catalytic amounts. This technology avoids the requirement of preactivation of the carboxylic acid or use of coupling reagents. Used to promote greener amidations of carboxylic acids and amines in catalytic amounts. This technology avoids the requirement of preactivation of the carboxylic acid or use of coupling reagents.Direct Amidation of Carboxylic Acids Catalyzed by ortho-Iodo Arylboronic Acids: Catalyst Optimization, Scope, and Preliminary Mechanistic Study Supporting a Peculiar Halogen Acceleration Effect.
Synonyms
(2-iodo-5-methoxyphenyl)boronic acid; (2-iodo-5-methoxyphenyl)boronic acid
IUPAC Name
(2-iodo-5-methoxyphenyl)boronic acid
SMILES
B(C1=C(C=CC(=C1)OC)I)(O)O
InChI
InChI=1S/C7H8BIO3/c1-12-5-2-3-7(9)6(4-5)8(10)11/h2-4,10-11H,1H3
InChI Key
XQYAEIDOJUNIGY-UHFFFAOYSA-N
Melting Point
202-207 °C
Flash Point
Not applicable
Purity
96 %
Storage
2-8 °C
LogP
-0.02040
Safety Information
Precautionary Statement
P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P312, P304+P340, P312, P322, P330, P363, and P501
Signal Word
Warning
Computed Properties
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
3
Rotatable Bond Count
2
Exact Mass
277.96112 g/mol
Monoisotopic Mass
277.96112 g/mol
Topological Polar Surface Area
49.7Ų
Heavy Atom Count
12
Formal Charge
0
Complexity
145
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-111995788-A | Polymer brush with bacterial responsiveness and preparation method thereof | 2020-04-26 |
| CN-111995788-B | Polymer brush with bacterial responsiveness and preparation method thereof | 2020-04-26 |
| CN-110155988-B | Activation method of carbon nano tube and method for preparing conductive heat-shrinkable tube | 2019-05-23 |
| CN-108409612-A | A kind of method that N- benzyl benzenesulfonamides are catalyzed and synthesized by boric acid/Catalyzed by Oxalic Acid system under microwave radiation | 2018-03-21 |
| EP-3344806-A1 | Glycan arrays and method of use | 2015-09-04 |
| JP-2018532990-A | Glycan arrays and methods of use | 2015-09-04 |
| KR-20180050339-A | Glycan arrays and how to use them | 2015-09-04 |
| TW-201721147-A | Glycan array and method of use thereof | 2015-09-04 |
| US-2017067885-A1 | Glycan arrays and method of use | 2015-09-04 |
| WO-2017041027-A1 | Glycan arrays and method of use | 2015-09-04 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 23013456 | 2012-10-05 | Direct amidation of carboxylic acids catalyzed by ortho-iodo arylboronic acids: catalyst optimization, scope, and preliminary mechanistic study supporting a peculiar halogen acceleration effect | The Journal of organic chemistry |
