2-Methoxypyridine-5-boronic acid pinacol ester
Product Information
Molecular Formula
C12H18BNO3
Molecular Weight
235.09
Description
2-Methoxypyridine-5-boronic acid pinacol ester is a biomedical product used in the development of drugs targeting various diseases. This compound acts as a boronic acid ester, enabling it to specifically interact with biological targets involved in disease processes. By incorporating this compound, researchers can enhance the medicinal properties and optimize the therapeutic efficacy of drugs against specific diseases.
Synonyms
2-Methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine, 2-Methoxy-5-pyridineboronic acid pinacol ester
IUPAC Name
2-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
SMILES
B1(OC(C(O1)(C)C)(C)C)C2=CN=C(C=C2)OC
InChI
InChI=1S/C12H18BNO3/c1-11(2)12(3,4)17-13(16-11)9-6-7-10(15-5)14-8-9/h6-8H,1-5H3
InChI Key
QOGNDJLSYMJGPP-UHFFFAOYSA-N
Boiling Point
321.823°C at 760 mmHg
Melting Point
47-51°C
Flash Point
216.0 °F - closed cup
Purity
95%
Density
1.067 g/cm3
Safety Information
Hazards
H315 - H319
Precautionary Statement
P305 + P351 + P338
Computed Properties
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
4
Rotatable Bond Count
2
Exact Mass
235.1379736 g/mol
Monoisotopic Mass
235.1379736 g/mol
Topological Polar Surface Area
40.6Ų
Heavy Atom Count
17
Formal Charge
0
Complexity
267
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-112794851-A | 3- (pyridine-3-yl) -7-azaindole derivative PI3K delta inhibitor and preparation method and application thereof | 2021-01-26 |
| WO-2022003712-A1 | Quinazolinones derivatives for treatment of non-alcoholic fatty liver disease, preparation and use thereof | 2020-06-29 |
| WO-2022005961-A1 | Prpk inhibitors | 2020-06-29 |
| US-2021346405-A1 | Bcl-2 inhibitors and their use as pharmaceuticals | 2020-04-28 |
| WO-2021120890-A1 | Pyrazolyl derivatives useful as anti-cancer agents | 2019-12-20 |
| WO-2021124222-A1 | Pyrazolyl derivatives useful as anti-cancer agents | 2019-12-20 |
| TW-202136241-A | Pyrazolyl derivatives useful as anti-cancer agents | 2019-12-20 |
| WO-2021074281-A1 | Substituted azacyles as trmp8 modulators | 2019-10-17 |
| CN-110437068-B | Preparation method of aromatic methylation | 2019-07-30 |
| CN-111808057-A | Suzuki reaction using alpha-O-alkenylsulfone as electrophile and use thereof | 2019-04-10 |
