2-(N-BOC)-5-(tributylstannyl)thiazole
Product Information
Molecular Formula
C20H38N2O2SSn
Molecular Weight
489.3
Description
2-(N-BOC)-5-(tributylstannyl)thiazole is a biomedical component predominantly employed in synthetic chemistry related to pharmaceuticals. It's instrumental in the creation of certain drugs, especially those deployed for neurological disorders and cancer treatments.
Synonyms
tert-Butyl-5-(tributylstannyl)thiazol-2-ylcarbamate
IUPAC Name
tert-butyl N-(5-tributylstannyl-1,3-thiazol-2-yl)carbamate
SMILES
CCCC[Sn](CCCC)(CCCC)C1=CN=C(S1)NC(=O)OC(C)(C)C
InChI
InChI=1S/C8H11N2O2S.3C4H9.Sn/c1-8(2,3)12-7(11)10-6-9-4-5-13-63*1-3-4-2/h4H,1-3H3,(H,9,10,11)3*1,3-4H2,2H3
InChI Key
WBQYLGCBVADFPD-LVHOJSJPAR
Melting Point
78-86 °C
Flash Point
Not applicable
Purity
96%
Safety Information
Hazards
H301 - H312 - H315 - H319 - H372 - H410
Precautionary Statement
P273 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P305 + P351 + P338 - P314
Computed Properties
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
4
Rotatable Bond Count
13
Exact Mass
490.167602 g/mol
Monoisotopic Mass
490.167602 g/mol
Topological Polar Surface Area
79.5Ų
Heavy Atom Count
26
Formal Charge
0
Complexity
393
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| WO-2022002102-A1 | Quinazoline compounds, preparation methods and uses thereof | 2020-06-30 |
| AU-2014368725-A1 | Isochromene derivatives as phosphoinositide 3-kinases inhibitors | 2013-12-18 |
| AU-2014368725-B2 | Isochromene derivatives as phosphoinositide 3-kinases inhibitors | 2013-12-18 |
| CA-2934135-A1 | Isochromene derivatives as phosphoinositide 3-kinases inhibitors | 2013-12-18 |
| EP-3083617-A1 | Isochromene derivatives as phosphoinositide 3-kinases inhibitors | 2013-12-18 |
| EP-3083617-B1 | Isochromene derivatives as phosphoinositide 3-kinases inhibitors | 2013-12-18 |
| JP-2017501146-A | Isochromene derivatives as phosphoinositide 3-kinase inhibitors | 2013-12-18 |
| JP-6617973-B2 | Isochromene derivatives as phosphoinositide 3-kinase inhibitors | 2013-12-18 |
| US-2015166549-A1 | Isochromene derivatives as phoshoinositide 3-kinases inhibitors | 2013-12-18 |
| US-9321776-B2 | Isochromene derivatives as phoshoinositide 3-kinases inhibitors | 2013-12-18 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 1176 | 1975-12-01 | Circadian variations of hormonal content in the nervous system of the crayfish | Comparative biochemistry and physiology. A, Comparative physiology |
