2-(Tributylstannyl)pyrazine
Product Information
Molecular Formula
C16H30N2Sn
Molecular Weight
369.12
Description
Microwave-assisted synthesis of substituted pyranones by palladium-catalyzed cross-coupling of arylstannanes with pyranyl triflates.
Synonyms
(2-Pyrazinyl)tributyltin,Tributylstannylpyrazine
IUPAC Name
tributyl(pyrazin-2-yl)stannane
SMILES
CCCC[Sn](CCCC)(CCCC)C1=NC=CN=C1
InChI
InChI=1S/C4H3N2.3C4H9.Sn/c1-2-6-4-3-5-13*1-3-4-2/h1-3H3*1,3-4H2,2H3
InChI Key
OVBXTKIWZAHFAC-LSKGPBBEAK
Boiling Point
130 °C/1 mmHg
Flash Point
235.4 °F - closed cup
Purity
95%
Density
1.1706 g/mL at 25 °C
Storage
−20°C
Refractive Index
n20/D 1.5158
Safety Information
Hazards
H301 - H312 - H315 - H319 - H372 - H410
Precautionary Statement
P273 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P305 + P351 + P338 - P314
Computed Properties
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
2
Rotatable Bond Count
10
Exact Mass
370.143102 g/mol
Monoisotopic Mass
370.143102 g/mol
Topological Polar Surface Area
25.8Ų
Heavy Atom Count
19
Formal Charge
0
Complexity
199
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| EP-3950683-A1 | Difluoromethyl-pyridin-2-yl triazoles | 2020-08-05 |
| WO-2022029170-A1 | Difluoromethyl-pyridin-2-yl triazoles | 2020-08-05 |
| WO-2022013408-A2 | Cyclic cyanoenone derivatives as modulators of keap1 | 2020-07-16 |
| WO-2021260109-A1 | A COMBINATION OF A CBP/p300 BROMODOMAIN INHIBITOR AND AN EGFR INHIBITOR FOR USE IN TREATING EGFR-MUTANT NSCLC | 2020-06-25 |
| WO-2021260110-A1 | Heterocyclic derivatives, pharmaceutical compositions and their use in the treatment, amelioration or prevention of fibrotic disease | 2020-06-25 |
| WO-2021260111-A1 | Combination of a cbp/p300 bromodomain inhibitor and a kras inhibitor for the treatment of cancer | 2020-06-25 |
| WO-2021249892-A1 | Substituted amino-pyrimidines | 2020-06-08 |
| WO-2021195781-A1 | Compounds, pharmaceutical compositions, and methods of preparing compounds and of their use | 2020-04-01 |
| WO-2021195782-A1 | Methods of using myt1 inhibitors | 2020-04-01 |
| WO-2021178780-A1 | Indazoles and azaindazoles as lrrk2 inhibitors | 2020-03-06 |
