3-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenylethynyl-trimethylsilane
Product Information
Molecular Formula
C17H25BO2Si
Description
3-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenylethynyl-trimethylsilane is an indispensable compound within the biomedical domain. It assumes a pivotal role in the fabrication of curative medications targeted towards an array of ailments. By virtue of its distinct constitution, it enables proficient amalgamation of pharmaceutical agents, specifically those devised for combating cancerous afflictions and neurodegenerative conditions. Possessing remarkable adaptability, this versatile compound exhibits auspicious prospects for propelling progress in biomedical investigations and therapeutic innovations.
Synonyms
4,4,5,5-Tetramethyl-2-[(3-trimethylsilylethynyl)phenyl]-[1,3,2]dioxaborolane
IUPAC Name
trimethyl-[2-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]ethynyl]silane
SMILES
B1(OC(C(O1)(C)C)(C)C)C2=CC(=CC=C2)C#C[Si](C)(C)C
InChI
InChI=1S/C17H25BO2Si/c1-16(2)17(3,4)20-18(19-16)15-10-8-9-14(13-15)11-12-21(5,6)7/h8-10,13H,1-7H3
InChI Key
LDKJXCOLGXLWKP-UHFFFAOYSA-N
Melting Point
86-90 °C
Flash Point
Not applicable
Purity
95%
Computed Properties
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
2
Rotatable Bond Count
3
Exact Mass
300.1716867 g/mol
Monoisotopic Mass
300.1716867 g/mol
Topological Polar Surface Area
18.5Ų
Heavy Atom Count
21
Formal Charge
0
Complexity
436
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| KR-20200012876-A | Paramycin Analogues as mTOR Inhibitors | 2017-05-02 |
| JP-2020518632-A | Rapamycin analogues as mTOR inhibitors | 2017-05-02 |
| US-2021094975-A1 | Rapamycin analogs as mtor inhibitors | 2017-05-02 |
| AU-2014274644-A1 | New thienopyrimidine derivatives, a process for their preparation and pharmaceutical compositions containing them | 2013-12-23 |
| DK-2886545-T3 | Thienopyrimidinderivater new, a process for their preparation and pharmaceutical compositions containing them | 2013-12-23 |
| EP-2886545-A1 | New thienopyrimidine derivatives, a process for their preparation and pharmaceutical compositions containing them | 2013-12-23 |
| EP-2886545-B1 | New thienopyrimidine derivatives, a process for their preparation and pharmaceutical compositions containing them | 2013-12-23 |
| HU-E029654-T2 | New thienopyrimidine derivatives, a process for their preparation and pharmaceutical compositions containing them | 2013-12-23 |
| JP-2015129120-A | Novel thienopyrimidine derivative, process for producing the same and pharmaceutical composition containing the same | 2013-12-23 |
| JP-5922215-B2 | Novel thienopyrimidine derivative, process for producing the same and pharmaceutical composition containing the same | 2013-12-23 |
