3-Amino-4-methylphenylboronic acid
Product Information
Molecular Formula
C7H10BNO2
Molecular Weight
150.97
Description
3-Amino-4-methylphenylboronic acid stands as an indispensable compound in the realm of biomedicine, signifying its paramount significance. Its utilization thrives within the realm of targeted therapies, specifically in the context of ailments like cancer, diabetes, and arthritis. In its role as a potent inhibitor, this compound exerts effective modulation over distinct signaling pathways, bestowing it with an irreplaceable utility in both drug discovery and treatment research.
Synonyms
(3-amino-4-methylphenyl)boronic acid; 3-Amino-4-methylbenzeneboronic acid; Boronic acid, (3-amino-4-methylphenyl)-; (3-amino-4-methyl-phenyl)boronic Acid; 3-Amino-4-methylphenylboranic acid; 3-amino4methyl phenyl boronic acid; 3-AMINO-P-TOLYLBORONIC ACID; 3-amino-4-methyl-phenylboronic acid; 3-amino-4-methyl phenyl boronic acid
IUPAC Name
(3-amino-4-methylphenyl)boronic acid
SMILES
B(C1=CC(=C(C=C1)C)N)(O)O
InChI
InChI=1S/C7H10BNO2/c1-5-2-3-6(8(10)11)4-7(5)9/h2-4,10-11H,9H2,1H3
InChI Key
PLTGUDDQNWJILD-UHFFFAOYSA-N
Flash Point
Not applicable
Computed Properties
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
3
Rotatable Bond Count
1
Exact Mass
151.0804587 g/mol
Monoisotopic Mass
151.0804587 g/mol
Topological Polar Surface Area
66.5Ų
Heavy Atom Count
11
Formal Charge
0
Complexity
132
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-114099416-A | Multifunctional injectable hydrogel with microenvironment response and preparation method and application thereof | 2021-10-28 |
| CN-111381458-A | Photoresist cleaning solution | 2018-12-27 |
| CN-111381459-A | Photoresist cleaning solution | 2018-12-27 |
| WO-2019234740-A1 | Mitogen-activated protein kinase kinase 7 inhibitors | 2018-06-04 |
| CA-3099847-A1 | Mitogen-activated protein kinase kinase 7 inhibitors | 2018-06-04 |
| CN-112236414-A | Mitogen-activated protein kinase 7 inhibitors | 2018-06-04 |
| EP-3802498-A1 | Mitogen-activated protein kinase kinase 7 inhibitors | 2018-06-04 |
| IL-279215-D0 | Inhibitors of the Mkk7-activated protein-mediated enzyme oriental enzyme | 2018-06-04 |
| JP-2021526139-A | Mightgen Activated Protein Kinase Kinase 7 Inhibitor | 2018-06-04 |
| US-2021238173-A1 | Mitogen-activated protein kinase kinase 7 inhibitors | 2018-06-04 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 4913 | 1976-01-01 | Action of beta-adrenergic blocking agents on the urethral pressure profile | Urologia internationalis |
| 3767 | 1975-12-31 | [Effects of adrenergic blockade on adipose tissue lipolysis provoked in cats and humans by intravenous perfusion of isoprenaline] | La Nouvelle presse medicale |
| 1775 | 1975-11-18 | Freezing and freeze-drying | Proceedings of the Royal Society of London. Series B, Biological sciences |
| 6 | 1975-10-27 | Studies of oxygen binding energy to hemoglobin molecule | Biochemical and biophysical research communications |
