3-phenyl-tetrahydro-pyran-2,6-dione
Product Information
Molecular Formula
C11H10O3
Molecular Weight
190.2
Description
3-phenyl-tetrahydro-pyran-2,6-dione is a key intermediate widely used in the biomedicine industry. It plays a crucial role in the synthesis of various drugs, including anti-inflammatory agents and antineoplastic agents. With its unique chemical structure, it exhibits potential drug effects in treating diseases such as rheumatoid arthritis and cancer.
Synonyms
(R,S)-3-Phenyl-dihydro-pyran-2,6-dione; 2H-Pyran-2,6(3H)-dione, dihydro-3-phenyl-; 2H-Pyran-2,6(3H)-dione,dihydro-3-phenyl-; 3-PHENYLDIHYDRO-2H-PYRAN-2,6(3H)-DIONE; ALPHA-PHENYLGLUTARIC ANHYDRIDE; AKOS MSC-0144
IUPAC Name
3-phenyloxane-2,6-dione
SMILES
C1CC(=O)OC(=O)C1C2=CC=CC=C2
InChI
InChI=1S/C11H10O3/c12-10-7-6-9(11(13)14-10)8-4-2-1-3-5-8/h1-5,9H,6-7H2
InChI Key
NVPRNSAYSSEIGR-UHFFFAOYSA-N
Boiling Point
218°C13 mm Hg(lit.)
Melting Point
95-99°C(lit.)
Purity
98%
Density
1.229g/cm3
Safety Information
Hazards
H315-H319-H335
Precautionary Statement
P261-P305 + P351 + P338
Computed Properties
XLogP3
1.6
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
3
Rotatable Bond Count
1
Exact Mass
190.062994177 g/mol
Monoisotopic Mass
190.062994177 g/mol
Topological Polar Surface Area
43.4Ų
Heavy Atom Count
14
Formal Charge
0
Complexity
241
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
1
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| WO-2022054737-A1 | Fluorinated carboxylic acid salt compound | 2020-09-08 |
| WO-2021235357-A1 | Electrolyte solution, electrochemical device, lithium ion secondary battery and module | 2020-05-22 |
| WO-2021235358-A1 | Electrolytic solution, electrochemical device, lithium-ion secondary battery, module, and compound | 2020-05-22 |
| JP-2021172711-A | Rubber composition for tires | 2020-04-22 |
| JP-2020143060-A | Non-aqueous electrolyte solution and non-aqueous electrolyte battery using it | 2020-04-07 |
| JP-6851527-B2 | Non-aqueous electrolyte solution and non-aqueous electrolyte battery using it | 2020-04-07 |
| WO-2021194908-A1 | Modified dipeptide cleavases, uses thereof and related kits | 2020-03-24 |
| US-2021174983-A1 | Compositions for the filling of high aspect ratio vertical interconnect access (via) holes | 2019-12-04 |
| WO-2021112933-A1 | Compositions for the filling of high aspect ratio vertical interconnect access (via) holes | 2019-12-04 |
| WO-2021095574-A1 | Electrode and electrochemical device | 2019-11-13 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 21773062 | 2011-04-01 | Synthesis and Biological Evaluation of New 3-Phenyl-1-[(4-arylpiperazin-1-yl)alkyl]-piperidine-2,6-diones | Scientia pharmaceutica |
| 18676209 | 2008-11-01 | Analysis and purification of alcohol-sensitive chiral compounds using 2,2,2-trifluoroethanol as a modifier in supercritical fluid chromatography | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences |
