4-CARBOXY-2,2,6,6-TETRAMETHYLPIPERIDINE 1-OXYL
Product Information
Molecular Formula
C10H18NO3 *
Molecular Weight
200.25
Description
4-carboxy-TEMPO is a member of the class of aminoxyls that is TEMPO carrying a carboxy group at position 4. It has a role as a radical scavenger, a MRI contrast agent and a spin label. It is a member of aminoxyls and a piperidinemonocarboxylic acid. It is functionally related to a TEMPO.
Synonyms
4-Carboxy-TEMPO
SMILES
CC1(CC(CC(N1[O])(C)C)C(=O)O)C
InChI
InChI=1S/C10H18NO3/c1-9(2)5-7(8(12)13)6-10(3,4)11(9)14/h7H,5-6H2,1-4H3,(H,12,13)
InChI Key
CYQGCJQJIOARKD-UHFFFAOYSA-N
Melting Point
178 °C
Purity
>97.0%(GC)(T)
Appearance
Peach to orange powder, crystals or fibers
Storage
Store under inert gas
Safety Information
Hazards
H315 H319
Precautionary Statement
P264 P280 P302 + P352 P337 + P313 P305 + P351 + P338 P362+P364 P332 + P313
Signal Word
Warning
Computed Properties
XLogP3
-1.3
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
3
Rotatable Bond Count
1
Exact Mass
200.12866844 g/mol
Monoisotopic Mass
200.12866844 g/mol
Topological Polar Surface Area
41.5Ų
Heavy Atom Count
14
Formal Charge
0
Complexity
230
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| US-2011019265-A1 | Display element and method of forming porous layer in display element | 2008-07-24 |
| US-2009156728-A1 | Modified butyl rubber composition | 2007-12-13 |
| US-2009093587-A1 | Modified butyl rubber composition | 2007-10-01 |
| US-7700695-B2 | Modified butyl rubber composition | 2007-10-01 |
| US-2008262147-A1 | Modified butyl rubber composition | 2007-04-19 |
| US-2010056723-A1 | Thermoplastic elastomer composition | 2006-12-13 |
| US-2009292044-A1 | Modified diene-based rubber and rubber composition containing the same | 2006-07-07 |
| US-2012029021-A1 | Nitroxide Free Radical Synergized Antineoplastic Agents | 2006-03-10 |
| US-2007093607-A1 | Modified butyl rubber composition | 2005-10-21 |
| US-7589155-B2 | Modified butyl rubber composition | 2005-10-21 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 34085520 | 2021-06-21 | Polyamine-Conjugated Nitroxides Are Efficacious Inhibitors of Oxidative Reactions Catalyzed by Endothelial-Localized Myeloperoxidase | Chemical research in toxicology |
| 15336310 | 2004-10-01 | The impact of carboxy nitroxide antioxidants on irradiated ataxia telangiectasia cells | Free radical biology & medicine |
