4-mercaptophenylboronic acid
Product Information
Molecular Formula
C6H7BO2S
Molecular Weight
153.99
Description
4-mercaptophenylboronic acid is a biomedical compound used for the treatment of various diseases. It exhibits remarkable potential in targeting cancer cells due to its inhibitory properties on tyrosine kinases. Additionally, it has shown efficacy in the treatment of diabetes by regulating glucose levels. This product plays a crucial role in biomedicine, especially in the development of targeted therapies for cancer and diabetes.
Synonyms
(4-sulfanylphenyl)boronic acid; 4-mercaptophenylboronicacid; Boronic acid, (4-mercaptophenyl)-; (4-mercaptophenyl)boronic acid; 4-mercaptophenyl boronic acid; 4-Mercaptobenzeneboronic Acid; 4-Mercaptophenylboronic acid, 90%; Boronic acid, B-(4-mercaptophenyl)-
IUPAC Name
(4-sulfanylphenyl)boronic acid
SMILES
B(C1=CC=C(C=C1)S)(O)O
InChI
InChI=1S/C6H7BO2S/c8-7(9)5-1-3-6(10)4-2-5/h1-4,8-10H
InChI Key
AUVSUPMVIZXUOG-UHFFFAOYSA-N
Melting Point
>230 °C (lit.)
Flash Point
Not applicable
Purity
90%
Density
1.27g/cm3
Computed Properties
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
3
Rotatable Bond Count
1
Exact Mass
154.0259808 g/mol
Monoisotopic Mass
154.0259808 g/mol
Topological Polar Surface Area
41.5Ų
Heavy Atom Count
10
Formal Charge
0
Complexity
102
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-114057782-A | Process method for synthesizing 4-mercapto phenylboronic acid | 2021-12-13 |
| CN-114177198-A | Nano-gold antibacterial agent and preparation method and application thereof | 2021-10-29 |
| CN-113945619-A | Preparation method and application of MPBA @ Au-MOF composite material photoelectrochemical sensor | 2021-10-18 |
| CN-113925974-A | Anticancer compound capable of targeting intestinal tumors and preparation method and application thereof | 2021-10-09 |
| CN-113897785-A | Preparation method of layer-by-layer self-assembled semiconductor fiber and transistor sensor | 2021-09-24 |
| CN-113892946-A | Preparation method of sweat sensing bandage based on SERS | 2021-09-17 |
| CN-113634240-A | Fluorescent magnetic composite nanofiber, and preparation method and application thereof | 2021-08-26 |
| CN-113599507-A | Preparation method of glucose-triggered active oxygen response injection type composite hydrogel | 2021-08-11 |
| CN-113533299-A | Microstructure optical fiber sensor | 2021-07-14 |
| CN-113563222-A | Method for detecting hydrogen peroxide based on surface enhanced Raman scattering of silent zone reporter molecule and application | 2021-07-13 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 22425223 | 2012-05-15 | Sensitive colorimetric visualization of dihydronicotinamide adenine dinucleotide based on anti-aggregation of gold nanoparticles via boronic acid-diol binding | Biosensors & bioelectronics |
| 22302165 | 2012-04-01 | Electrochemically synthesized polymers in molecular imprinting for chemical sensing | Analytical and bioanalytical chemistry |
| 21088793 | 2011-01-14 | Synthesis, carbohydrate- and DNA-binding studies of cationic 2,2':6',2''-terpyridineplatinum(II) complexes containing N- and S-donor boronic acid ligands | Dalton transactions (Cambridge, England : 2003) |
| 20369262 | 2010-10-01 | Electrochemical recognition for sugars on the chitosan-poly(diallyldimethylammonium chloride)-nano-Prussian blue/nano-Au/4-mercaptophenylboronic acid modified glassy carbon electrode | Bioprocess and biosystems engineering |
| 20170134 | 2010-03-15 | Surface plasmon resonance analysis of antibiotics using imprinted boronic acid-functionalized Au nanoparticle composites | Analytical chemistry |
| 19834891 | 2009-11-01 | On-plate-selective enrichment of glycopeptides using boronic acid-modified gold nanoparticles for direct MALDI-QIT-TOF MS analysis | Proteomics |
| 19844974 | 2009-11-01 | Facile synthesis of 4-mercaptophenylboronic acid functionalized gold nanoparticles for selective enrichment of glycopeptides | Rapid communications in mass spectrometry : RCM |
| 20027646 | 2009-09-01 | Piezoresistive cantilever array sensor for consolidated bioprocess monitoring | Scanning |
| 19472289 | 2009-05-01 | Synthesis and application of novel phenylboronate affinity materials based on organic polymer particles for selective trapping of glycoproteins | Journal of separation science |
| 18522434 | 2008-07-01 | Label-free sugar detection using phenylboronic acid-functionalized piezoresistive microcantilevers | Analytical chemistry |
