4-Methoxypicolinimidamide hydrochloride
Product Information
Molecular Formula
C7H10ClN3O
Molecular Weight
187.63
Description
This pyridyl carboxamidine ligand has been demonstrated by Daniel Weix's lab to enable nickel-catalyzed cross-coupling of diverse basic nitrogen heterocycles with primary and secondary alkyl halides.
Synonyms
Weix 2-pyridylcarboxamidine ligand for nickel catalysis
IUPAC Name
4-methoxypyridine-2-carboximidamidehydrochloride
SMILES
COC1=CC(=NC=C1)C(=N)N.Cl
InChI
InChI=1S/C7H9N3O.ClH/c1-11-5-2-3-10-6(4-5)7(8)9/h2-4H,1H3,(H3,8,9)1H
InChI Key
JOUDWIBACXLPIO-UHFFFAOYSA-N
Melting Point
174-176 °C
Flash Point
Not applicable
Purity
≥95%
Computed Properties
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
3
Rotatable Bond Count
2
Exact Mass
187.0512396 g/mol
Monoisotopic Mass
187.0512396 g/mol
Topological Polar Surface Area
72Ų
Heavy Atom Count
12
Formal Charge
0
Complexity
149
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
2
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| EP-3892615-A1 | Process for the preparation of silodosin | 2020-04-09 |
| WO-2021205023-A1 | Process for the preparation of silodosin | 2020-04-09 |
| US-2020339559-A1 | Heterocyclic compounds and their use for treatment of helminthic infections and diseases | 2019-04-26 |
| WO-2020219871-A1 | Heterocyclic compounds and their use for treatment of helminthic infections and diseases | 2019-04-26 |
| CN-114072395-A | Heterocyclic compounds and their use for treating helminth infections and diseases | 2019-04-26 |
| EP-3959207-A1 | Heterocyclic compounds and their use for treatment of helminthic infections and diseases | 2019-04-26 |
| WO-2020165834-A1 | Substituted 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof | 2019-02-15 |
| AU-2020222346-A1 | Substituted 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof | 2019-02-15 |
| CA-3123519-A1 | Substituted 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof | 2019-02-15 |
| AU-2020222346-B2 | Substituted 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof | 2019-02-15 |
