5,5',6,6'-TETRAHYDROXY-3,3,3',3'-TETRAMETHYL-1,1'-SPIROBISINDANE
Product Information
Molecular Formula
C21H24O4
Molecular Weight
340.41
Description
5,5',6,6'-Tetrahydroxy-3,3,3',3'-tetramethyl-1,1'-spirobisindane is an intriguing compound extensively utilized in the biomedical industry and showcases exceptional promise for combating an array of ailments, encompassing cancer and neurodegenerative disorders. Owing to its peculiar molecular architecture, this substance manifests remarkable therapeutic properties, propelling it as an auspicious contender meriting further scrutiny and advancement in the realm of pharmaceutical innovation.
Synonyms
LABOTEST-BB LT00160134; 5,5',6,6'-TETRAHYDROXY-3,3,3',3'-TETRAMETHYL-1,1'-SPIROBIINDAN; 5,5',6,6'-TETRAHYDROXY-3,3,3',3'-TETRAMETHYL-1,1'-SPIROBISINDAN; 5,5',6,6'-TETRAHYDROXY-3,3,3',3'-TETRAMETHYL-1,1'-SPIROBISINDANE; 5,5',6,6'-TETRAHYDROXY-3,3,3',3'-TETRAM
IUPAC Name
1,1,1',1'-tetramethyl-3,3'-spirobi[2H-indene]-5,5',6,6'-tetrol
SMILES
CC1(CC2(CC(C3=CC(=C(C=C32)O)O)(C)C)C4=CC(=C(C=C41)O)O)C
InChI
InChI=1S/C21H24O4/c1-19(2)9-21(13-7-17(24)15(22)5-11(13)19)10-20(3,4)12-6-16(23)18(25)8-14(12)21/h5-8,22-25H,9-10H2,1-4H3
InChI Key
POFMQEVZKZVAPQ-UHFFFAOYSA-N
Boiling Point
561.2°C at 760 mmHg
Melting Point
300°C
Purity
98%
Density
1.37g/cm3
Safety Information
Hazards
H315 - H319 - H335
Precautionary Statement
P302 + P352 - P305 + P351 + P338
Computed Properties
XLogP3
5.1
Hydrogen Bond Donor Count
4
Hydrogen Bond Acceptor Count
4
Rotatable Bond Count
0
Exact Mass
340.16745924 g/mol
Monoisotopic Mass
340.16745924 g/mol
Topological Polar Surface Area
80.9Ų
Heavy Atom Count
25
Formal Charge
0
Complexity
494
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-113713636-A | Mixed matrix membrane based on PIM-1 and preparation method thereof | 2021-08-27 |
| CN-113578068-A | Novel C2NxO1-xPer-poly-imine-1 (PIM-1) mixed matrix membrane and preparation method and application thereof | 2021-08-19 |
| CN-113842783-A | Acid-resistant high-flux polyarylether composite nanofiltration membrane, and preparation method and application thereof | 2021-08-02 |
| CN-113522040-A | Method for preparing high-performance carbon dioxide separation composite membrane containing twisted structure through interfacial polymerization | 2021-07-30 |
| CN-113717361-A | Method for preparing polyester film through gas-phase polymerization, polyester film and application | 2021-07-27 |
| CN-113429765-A | Degradable PLA/PIM-1 air-conditioning film and preparation method and application thereof | 2021-06-16 |
| CN-113024799-A | Application of soluble polymer with micropores in iodine vapor detection | 2021-03-01 |
| CN-112920447-A | Preparation method of polymer membrane with micropores and capable of being hydrolyzed and crosslinked simultaneously | 2021-02-17 |
| CN-112920447-B | Preparation method of polymer membrane with micropores and capable of being hydrolyzed and crosslinked simultaneously | 2021-02-17 |
| CN-112812292-A | Preparation method and application of polymer molecular sieve for gas separation and mixed matrix membrane thereof | 2020-12-28 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 16355434 | 2006-01-23 | Tetraanionic organoborate squares glued together by cations to generate nanotubular stacks | Angewandte Chemie (International ed. in English) |
| 10821715 | 2000-05-18 | A new class of HIV-1 integrase inhibitors: the 3,3,3', 3'-tetramethyl-1,1'-spirobi(indan)-5,5',6,6'-tetrol family | Journal of medicinal chemistry |
| 9736543 | 1998-09-01 | Human immunodeficiency virus type 1 cDNA integration: new aromatic hydroxylated inhibitors and studies of the inhibition mechanism | Antimicrobial agents and chemotherapy |
