5-Chloro-2-methoxyphenylboronic Acid
Product Information
Molecular Formula
C7H8ClO3B
Molecular Weight
186.40
Description
Reactant for: Boron-Heck arylation; Suzuki-Miyaura reaction.
Synonyms
(5-chloro-2-methoxyphenyl)boronic acid; (5-chloro-2-methoxyphenyl)boronic acid
IUPAC Name
(5-chloro-2-methoxyphenyl)boronic acid
SMILES
B(C1=C(C=CC(=C1)Cl)OC)(O)O
InChI
InChI=1S/C7H8BClO3/c1-12-7-3-2-5(9)4-6(7)8(10)11/h2-4,10-11H,1H3
InChI Key
FMBVAOHFMSQDGT-UHFFFAOYSA-N
Boiling Point
360.2 °C at 760 mmHg
Melting Point
134-141 °C (lit.)
Density
1.32 g/cm3
Appearance
White powder
LogP
0.02840
Safety Information
Precautionary Statement
P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501
Signal Word
Warning
Computed Properties
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
3
Rotatable Bond Count
2
Exact Mass
186.0255020 g/mol
Monoisotopic Mass
186.0255020 g/mol
Topological Polar Surface Area
49.7Ų
Heavy Atom Count
12
Formal Charge
0
Complexity
145
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-113861188-A | Pyrazolo [3,4-b ] pyridine derivative, preparation method thereof and application thereof as HPK1 inhibitor | 2021-08-23 |
| CN-113683628-A | Organic electroluminescent material, electronic element, and electronic device | 2021-02-09 |
| CN-111777586-A | Preparation method of 10-chlorobenzo [ kl ] xanthene compound | 2020-07-29 |
| US-2022048930-A1 | Inhibitors of complement factors and uses thereof | 2020-07-20 |
| WO-2022020244-A1 | Inhibitors of complement factors and uses thereof | 2020-07-20 |
| KR-20220010455-A | Organic light emitting device | 2020-07-17 |
| WO-2022015107-A1 | Organic light-emitting device | 2020-07-17 |
| WO-2021115335-A1 | Compound as cyclin-dependent kinase 9 inhibitor and use thereof | 2019-12-09 |
| KR-20210046568-A | Organic light emitting device | 2019-10-18 |
| WO-2021075895-A1 | Organic light-emitting device | 2019-10-18 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 1198 | 1975-12-01 | An oxygen dependent current in Aplysia neurons: an approach to the question of cellular hypoxic adaptation | Comparative biochemistry and physiology. A, Comparative physiology |
