5-Fluoro-2-methoxyphenylboronic acid
Product Information
Molecular Formula
C7H8BFO3
Molecular Weight
169.94
Description
Reactant for:• Suzuki couplings• Copper catalyzed arylation
Synonyms
2-Methoxy-5-fluorophenylboronic acid
IUPAC Name
(5-fluoro-2-methoxyphenyl)boronic acid
SMILES
B(C1=C(C=CC(=C1)F)OC)(O)O
InChI
InChI=1S/C7H8BFO3/c1-12-7-3-2-5(9)4-6(7)8(10)11/h2-4,10-11H,1H3
InChI Key
CCQKIRUMTHHPSX-UHFFFAOYAN
Melting Point
144-153 °C (lit.)
Flash Point
Not applicable
Purity
98%
Computed Properties
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
4
Rotatable Bond Count
2
Exact Mass
170.0550524 g/mol
Monoisotopic Mass
170.0550524 g/mol
Topological Polar Surface Area
49.7Ų
Heavy Atom Count
12
Formal Charge
0
Complexity
145
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-113563275-A | Preparation and application of aminopyrimidine derivatives selectively targeting CDK9 | 2021-07-27 |
| WO-2021201576-A1 | Benzothiazole derivative compound | 2020-03-30 |
| KR-20210122192-A | Compounds of Benzothiazole Derivatives | 2020-03-30 |
| WO-2021126693-A1 | Gem-disubstituted piperidine melanocortin subtype-2 receptor (mc2r) antagonists and uses thereof | 2019-12-18 |
| CN-112094165-A | Method for preparing biaryl compound by Suzuki coupling reaction | 2019-06-18 |
| CN-112079829-A | 1,2, 4-triazole [4,3-a ] pyridine derivative and preparation method and application thereof | 2019-06-14 |
| CN-112079829-B | 1,2, 4-triazole [4,3-a ] pyridine derivative and preparation method and application thereof | 2019-06-14 |
| WO-2020205991-A1 | TOPOISOMERASE II-alpha INHIBITORS AND METHODS OF TREATING CANCER USING THE SAME | 2019-04-01 |
| WO-2020151589-A1 | Acylamino bridged heterocyclic compound, and composition and application thereof | 2019-01-25 |
| TW-202041507-A | Amido bridged heterocyclic compound, and composition and application thereof | 2019-01-25 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 1175 | 1975-12-01 | The effect of splenectomy on the hematology and on the activity of delta-aminolevulinic acid dehydratase (ALA-D) in hemopoietic tissues of the dogfish, Scyliorhinus canicula (Elasmobranchii) | Comparative biochemistry and physiology. A, Comparative physiology |
