Bromomaleic Anhydride
Product Information
Molecular Formula
C4HBrO3
Molecular Weight
176.95
Description
Bromomaleic Anhydride (CAS# 5926-51-2) is used to study reversible or permanent chemical modification of proteins and peptides by control of maleimide hydrolysis.
Synonyms
3-bromofuran-2,5-dione; 3-bromofuran-2,5-dione
IUPAC Name
3-bromofuran-2,5-dione
SMILES
C1=C(C(=O)OC1=O)Br
InChI
InChI=1S/C4HBrO3/c5-2-1-3(6)8-4(2)7/h1H
InChI Key
YPRMWCKXOZFJGF-UHFFFAOYSA-N
Boiling Point
215 °C (lit.)
Flash Point
235.4 °CF - closed cup
Purity
97 %
Density
1.905 g/mL at 25 °C (lit.)
Appearance
Colorless liquid
Refractive Index
n20/D 1.54 (lit.)
LogP
0.34860
Safety Information
Hazards
H315 - H319 - H335
Precautionary Statement
P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501
Signal Word
Warning
Computed Properties
XLogP3
0.8
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
3
Rotatable Bond Count
0
Exact Mass
175.91091 g/mol
Monoisotopic Mass
175.91091 g/mol
Topological Polar Surface Area
43.4Ų
Heavy Atom Count
8
Formal Charge
0
Complexity
182
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-114031544-A | Substituted maleimide fluorescent compound and preparation and application thereof | 2021-10-08 |
| CN-113003981-A | Superfine composite mineral admixture grinding aid and preparation method thereof | 2021-04-19 |
| JP-2021066746-A | Conjugates of cytotoxic agents and cell-binding receptors | 2021-02-04 |
| CN-111944134-A | Preparation method of high molecular weight unsaturated polyester and product thereof | 2020-08-24 |
| CN-111944134-B | Preparation method of high molecular weight unsaturated polyester and product thereof | 2020-08-24 |
| US-2022048909-A1 | Heteroaryl substituted spiropiperidinyl derivatives and pharmaceutical uses thereof | 2020-08-14 |
| WO-2022034529-A1 | Heteroaryl substituted spiropiperidinyl derivatives and pharmaceutical uses thereof | 2020-08-14 |
| WO-2021262830-A1 | Silicone elastomer compositions | 2020-06-24 |
| CN-111635473-A | Method for regulating and controlling product dispersity of reversible addition-fragmentation chain transfer polymerization method | 2020-06-17 |
| WO-2021236885-A1 | Piperidine-2,6-diones as small molecule degraders of helios and methods of use | 2020-05-21 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 22095664 | 2012-01-02 | Bromomaleimide-linked bioconjugates are cleavable in mammalian cells | Chembiochem : a European journal of chemical biology |
| 20857948 | 2010-10-15 | A colorimetric proton sponge | The Journal of organic chemistry |
