Cphos
Product Information
Molecular Formula
C28H41N2P
Molecular Weight
436.61
Description
CPhos can be used:• As a ligand in the Pd-catalyzed synthesis of 3-cyclopentylindole derivatives, dihydrobenzofurans and trans-bicyclic sulfamides.• To synthesize palladacycle precatalysts for Negishi coupling of secondary alkylzinc.
Synonyms
2-Dicyclohexylphosphino-2',6'-bis(N,N-dimethylamino)biphenyl
IUPAC Name
2-(2-dicyclohexylphosphanylphenyl)-1-N,1-N,3-N,3-N-tetramethylbenzene-1,3-diamine
SMILES
CN(C)C1=C(C(=CC=C1)N(C)C)C2=CC=CC=C2P(C3CCCCC3)C4CCCCC4
InChI
InChI=1S/C28H41N2P/c1-29(2)25-19-13-20-26(30(3)4)28(25)24-18-11-12-21-27(24)31(22-14-7-5-8-15-22)23-16-9-6-10-17-23/h11-13,18-23H,5-10,14-17H2,1-4H3
InChI Key
DRNAQRXLOSUHBQ-UHFFFAOYSA-N
Melting Point
108-113 °C
Flash Point
Not applicable
Purity
98%
Safety Information
Hazards
H315 - H319 - H335
Precautionary Statement
P302 + P352 - P305 + P351 + P338
Signal Word
Warning
Computed Properties
XLogP3
7
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
2
Rotatable Bond Count
6
Exact Mass
436.30073631 g/mol
Monoisotopic Mass
436.30073631 g/mol
Topological Polar Surface Area
6.5Ų
Heavy Atom Count
31
Formal Charge
0
Complexity
489
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| JP-2021075535-A | Chemical methods for preparing pyrimidine derivatives and their intermediates | 2021-01-14 |
| CN-112778267-A | Thiophene-3 (2H) -ketone compound and synthetic method thereof | 2020-12-31 |
| CN-112457267-A | Preparation method of isoxazoline insecticide | 2020-11-27 |
| WO-2022051567-A1 | Substituted pyrido[2,3-b]pyrazinones and reuated compounds and their use in treating medicau conditions | 2020-09-04 |
| US-2022064375-A1 | Polyesters and Polyketoesters from Carbonylative Terpolymerization of enols, Methods to Produce, Blends, and Articles Therefrom | 2020-09-01 |
| WO-2022028586-A1 | Compounds as c5ar inhibitors | 2020-08-07 |
| WO-2022006543-A1 | 5-[5-(piperidin-4-yl)thieno[3,2-c]pyrazol-2-yl]indazole derivatives and related compounds as modulators for splicing nucleic acids and for the treatment of proliferative diseases | 2020-07-02 |
| WO-2021255698-A1 | Heterocyclic compound and an organic electroluminescence device comprising the heterocyclic compound | 2020-06-19 |
| JP-2021195367-A | Cyclopropyldihydroquinoline sulfonamide compound | 2020-06-10 |
| JP-2021195368-A | Cyclobutyldihydroquinoline sulfonamide compound | 2020-06-10 |
