Dextran
| Catalog Number | Size | Price | Stock | Quantity |
|---|---|---|---|---|
| BPM-079228 | 100 g | $199 | In stock |
Product Information
Molecular Formula
(C6H10O5)n
Description
Dextran is a complex branched polysaccharide composed primarily of α-1,6-linked D-glucose units with occasional α-1,3 branches. Supplied as a fine powder, it exhibits high water solubility and forms viscous solutions, making it ideal for diverse biochemical applications. Its unique molecular structure facilitates use as a stabilizing agent, osmotic regulator, and molecular size marker in chromatography. Widely employed in cell culture, enzyme immobilization, and separation technologies, Dextran supports advanced research in biochemistry, molecular biology, and analytical chemistry.
Synonyms
Polyglusol; Dextrans; Detrax 40; Dextran T 20; Dextran T 70; Dextranen; Dextraven; Eudextran; Expandex; Gentran; Gentran 40; Hemodex; Hyscon; Hyskon; Infucoll; Intrader; Intradex; LMD; LMWD; Longasteril 70; LVD; Macrodex; Macrose; Oncovertin N; Onkotin; PL 1S; Plasmafusin; Plasmodex; Plavolex; Polyglucin; Promit; R-gel; Rheodextran; Rheoisodex; Rheomacrodex; Rheopolyglucin; Rheopolyglucine; Rheorondex; Rheotran; Rondex; Rondex (polysaccharide); Serva G; T 40; T 40 (polysaccharide); T 70 (carbohydrate); Ultradex; Ultradex 530; Ultradex 531; α-Dextran
Melting Point
80 °C (dec.)
Density
1.042 g/cm3
Solubility
Soluble in Water (100 mg/ml), DMSO (freely), Formamide (Freely), Ethylene Glycol (Freely), Glycerol (Freely)
Appearance
White to Off-white Powder
Application
Bacteria growing on a sucrose substrate produce this polysaccharide, which is composed of alpha-D-glucopyranosyl units with different branching and chain lengths; Used in soft center confections, as a barley malt substitute, and as a plasma volume expander; Mixed ethers and esters can be used in lacquers; Used as a formulation and processing aid, stabilizer or thickener, surface finishing agent, and texturizer for foods.
Storage
Store at RT
Stability
Stable. Keep dry. Incompatible with strong oxidizing agents.
LogP
-7.73040
Safety Information
Hazards
Harmless-use normal precautions
Handling
Exercise normal care
QC Data
| Molecular Weight | Viscosity | Description |
|---|---|---|
| Mw~200,000-300,000 | i.v. 0.4-0.5 | Water soluble carbohydrate with many pharmaceutical and technical uses. |
| Mw~100,000-200,000 | i.v. 0.343 | Water soluble carbohydrate with many pharmaceutical and technical uses. |
| Mw~15,000-20,000 | i.v. 0.10-0.14 | Water soluble carbohydrate with many pharmaceutical and technical uses. |
Computed Properties
XLogP3
-7.2
Hydrogen Bond Donor Count
11
Hydrogen Bond Acceptor Count
16
Rotatable Bond Count
11
Exact Mass
504.16903493 g/mol
Monoisotopic Mass
504.16903493 g/mol
Topological Polar Surface Area
277Ų
Heavy Atom Count
34
Formal Charge
0
Complexity
625
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
14
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| WO-2020161273-A1 | Compositions for cryopreservation of a biological material | 2019-02-07 |
| AU-2020219416-A1 | Compositions for cryopreservation of a biological material | 2019-02-07 |
| CA-3126266-A1 | Compositions for cryopreservation of a biological material | 2019-02-07 |
| KR-20210113649-A | Compositions for cryopreservation of biological materials | 2019-02-07 |
| EP-3920696-A1 | Compositions for cryopreservation of a biological material | 2019-02-07 |
| JP-2020507752-A | Methods for adjusting signal intensity in interaction assays | 2017-01-27 |
| AU-2015347361-A1 | New dextran sulfate | 2014-11-11 |
| AU-2015347361-B2 | New dextran sulfate | 2014-11-11 |
| CA-2967264-A1 | New dextran sulfate | 2014-11-11 |
| CA-2967264-C | New dextran sulfate | 2014-11-11 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 34627954 | 2021-12-15 | Trimellitic anhydride facilitates transepithelial permeability disrupting tight junctions in sinonasal epithelial cells | Toxicology letters |
| 30102254 | 2018-08-31 | Intestinal P-glycoprotein exports endocannabinoids to prevent inflammation and maintain homeostasis | The Journal of clinical investigation |
| 27474066 | 2016-09-25 | Anti-inflammatory and antiedematogenic activity of the Ocimum basilicum essential oil and its main compound estragole: In vivo mouse models | Chemico-biological interactions |
| 27217748 | 2016-01-01 | Oxidative stress response in neural stem cells exposed to different superparamagnetic iron oxide nanoparticles | International journal of nanomedicine |
| 25878373 | 2015-03-01 | Differential effects of dexamethasone and rosiglitazone in a sephadex-induced model of lung inflammation in rats: possible role of tissue inhibitor of metalloproteinase-3 | Indian journal of pharmacology |
| 26576301 | 2015-01-01 | Assessment of Immunotoxicity of Dextran Coated Ferrite Nanoparticles in Albino Mice | Molecular biology international |
| 25019507 | 2014-01-01 | Increased gut permeability and bacterial translocation after chronic chlorpyrifos exposure in rats | PloS one |
| 23872256 | 2013-10-05 | Evaluation of the anti-inflammatory activity of riparin II (O-methil-N-2-hidroxi-benzoyl tyramine) in animal models | Chemico-biological interactions |
| 23816874 | 2013-10-01 | Antifungal property of hibicuslide C and its membrane-active mechanism in Candida albicans | Biochimie |
| 23044124 | 2013-01-02 | Mutational analysis and characterization of dextran synthesizing enzyme from wild and mutant strain of Leuconostoc mesenteroides | Carbohydrate polymers |
