Dextran

Catalog Number Size Price Stock Quantity
B1999-079228 100 g $199 In stock
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Product Information

Molecular Formula:
(C6H10O5)n
Molecular Weight:
504.4
Description
Dextrans are long-chain glucose polysaccharides of various relative molecular mass.
Synonyms
Polyglusol
IUPAC Name
2,3,4,5-tetrahydroxy-6-[3,4,5-trihydroxy-6-[[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl]oxyhexanal
Canonical SMILES
C(C1C(C(C(C(O1)OCC2C(C(C(C(O2)OCC(C(C(C(C=O)O)O)O)O)O)O)O)O)O)O)O
InChI
InChI=1S/C18H32O16/c19-1-5(21)9(23)10(24)6(22)3-31-17-16(30)14(28)12(26)8(34-17)4-32-18-15(29)13(27)11(25)7(2-20)33-18/h1,5-18,20-30H,2-4H2
InChI Key
FZWBNHMXJMCXLU-UHFFFAOYSA-N
Melting Point
>254ºC
Solubility
Soluble in Water (100 mg/ml), DMSO (freely), Formamide (Freely), Ethylene Glycol (Freely), Glycerol (Freely)
Appearance
White to Off-white Powder
Application
Bacteria growing on a sucrose substrate produce this polysaccharide, which is composed of alpha-D-glucopyranosyl units with different branching and chain lengths; Used in soft center confections, as a barley malt substitute, and as a plasma volume expander; Mixed ethers and esters can be used in lacquers; Used as a formulation and processing aid, stabilizer or thickener, surface finishing agent, and texturizer for foods.
Storage
Store at RT
Stability
Stable. Keep dry. Incompatible with strong oxidizing agents.
LogP
-7.73040

Safety Information

Hazards
Harmless-use normal precautions
Handling
Exercise normal care
Molecular WeightViscosityDescription
Mw~200,000-300,000 i.v. 0.4-0.5 Water soluble carbohydrate with many pharmaceutical and technical uses.
Mw~100,000-200,000 i.v. 0.343 Water soluble carbohydrate with many pharmaceutical and technical uses.
Mw~15,000-20,000 i.v. 0.10-0.14 Water soluble carbohydrate with many pharmaceutical and technical uses.

Computed Properties

XLogP3
-7.2
Hydrogen Bond Donor Count
11
Hydrogen Bond Acceptor Count
16
Rotatable Bond Count
11
Exact Mass
504.16903493 g/mol
Monoisotopic Mass
504.16903493 g/mol
Topological Polar Surface Area
277Ų
Heavy Atom Count
34
Formal Charge
0
Complexity
625
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
14
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes

Patents

Publication Number Title Priority Date
WO-2020161273-A1 Compositions for cryopreservation of a biological material 2019-02-07
AU-2020219416-A1 Compositions for cryopreservation of a biological material 2019-02-07
CA-3126266-A1 Compositions for cryopreservation of a biological material 2019-02-07
KR-20210113649-A Compositions for cryopreservation of biological materials 2019-02-07
EP-3920696-A1 Compositions for cryopreservation of a biological material 2019-02-07
JP-2020507752-A Methods for adjusting signal intensity in interaction assays 2017-01-27
AU-2015347361-A1 New dextran sulfate 2014-11-11
AU-2015347361-B2 New dextran sulfate 2014-11-11
CA-2967264-A1 New dextran sulfate 2014-11-11
CA-2967264-C New dextran sulfate 2014-11-11

Literatures

PMID Publication Date Title Journal
34627954 2021-12-15 Trimellitic anhydride facilitates transepithelial permeability disrupting tight junctions in sinonasal epithelial cells Toxicology letters
30102254 2018-08-31 Intestinal P-glycoprotein exports endocannabinoids to prevent inflammation and maintain homeostasis The Journal of clinical investigation
27474066 2016-09-25 Anti-inflammatory and antiedematogenic activity of the Ocimum basilicum essential oil and its main compound estragole: In vivo mouse models Chemico-biological interactions
27217748 2016-01-01 Oxidative stress response in neural stem cells exposed to different superparamagnetic iron oxide nanoparticles International journal of nanomedicine
25878373 2015-03-01 Differential effects of dexamethasone and rosiglitazone in a sephadex-induced model of lung inflammation in rats: possible role of tissue inhibitor of metalloproteinase-3 Indian journal of pharmacology
26576301 2015-01-01 Assessment of Immunotoxicity of Dextran Coated Ferrite Nanoparticles in Albino Mice Molecular biology international
25019507 2014-01-01 Increased gut permeability and bacterial translocation after chronic chlorpyrifos exposure in rats PloS one
23872256 2013-10-05 Evaluation of the anti-inflammatory activity of riparin II (O-methil-N-2-hidroxi-benzoyl tyramine) in animal models Chemico-biological interactions
23816874 2013-10-01 Antifungal property of hibicuslide C and its membrane-active mechanism in Candida albicans Biochimie
23044124 2013-01-02 Mutational analysis and characterization of dextran synthesizing enzyme from wild and mutant strain of Leuconostoc mesenteroides Carbohydrate polymers
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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